Mental Health

Turning off your smartphone at night can make you more productive at work

What does it mean for you?

Switching off your smartphone at night means better productivity at work the next day.

‘Smartphones are almost perfectly designed to disrupt sleep,’ said Russell Johnson, assistant professor of management at Michigan State University in the US.

‘Because they keep us mentally engaged late into the evening, they make it hard to detach from work so we can relax and fall asleep,’ he warned.

How was the study conducted?

In a pair of studies surveying a broad spectrum of workers, his team found that people who monitored their smartphones for business purposes after 9 p.m. were more tired and were less engaged the following day on the job.

Many of us consider the devices to be among the most important tools ever invented when it comes to increasing productivity of knowledge-based work, said the research published in the journal Organisational Behaviour and Human Decision Processes.

For the first study, the researchers had 82 upper-level managers complete multiple surveys every day for two weeks.

The second study surveyed 161 employees daily in a variety of occupations – from nursing to manufacturing and from accounting to dentistry.

Across both studies, the surveys showed that night-time smartphone usage for business purposes cut into sleep and sapped workers’ energy the next day in the office. (Read: Lower brightness of smartphones to get better sleep)

Why are smartphones bad for sleep?

In addition to keeping people mentally engaged at night, smartphones emit ‘blue light’ that appears to be the most disruptive of all colours of light.

Blue light is known to hinder melatonin, a chemical in the body that promotes sleep, Johnson said.

‘The night-time use of smartphones appears to have both psychological and physiological effects on people’s ability to sleep and on sleep’s essential recovery functions,’ he added.

Source: newsr

Many hospitalized older people need decision help

When the time comes for making critical medical decisions while in the hospital, a new study says older people often rely on family members or other surrogates to make those calls.

Researchers found that about half of the older patients they tracked needed help making decisions within two days of being admitted to the hospital.

Considering the aging U.S. population and the mental burden borne by the family and friends making those decisions, the study’s lead author told Reuters Health that hospitals should work to accommodate surrogate decision makers.

“The long-term goal would be to improve hospital processes,” Dr. Alexia Torke, a center scientist at the Indiana University Center for Aging Research in Indianapolis, told Reuters Health.

Previous studies have examined the role of surrogate decision makers in some medical settings, but Torke and her colleagues write in JAMA Internal Medicine that they couldn’t find research showing how often people rely on others to make decisions while in the hospital.

“We set out to describe the scope of the problem as a whole,” Torke said.

For the study, she and her fellow researchers analyzed data on people who were over 65 years old and admitted to either of two hospitals in one Midwestern city between November 2008 and December 2011.

To be included in the study, a person had to have been hospitalized for 48 hours. After that time, a doctor was interviewed about the decision making process for that patient. Other information was taken from the patient’s medical record.

Of 1,598 study participants, the researchers found that 1,083 faced at least one major medical decision that was discussed with the patient or a surrogate.

Of those cases, about 570 patients made all of their decisions alone, 264 made their decisions with the help of a surrogate and surrogates made all of the decisions for 249 patients.

Most patients with surrogates were in the hospitals’ general wards, not the intensive care units.

Surrogate decision makers were most often the patients’ daughters, followed by sons and spouses.

Within the first two days of patients being admitted to the hospital, the researchers found that about 60 percent of surrogates had to make decisions about life-sustaining treatments and about half had to make decisions about operations and where the patients would go after leaving the hospital.

The study participants who required the help of a surrogate were also most likely to have worse outcomes. They were more likely to need a ventilator or a feeding tube, to be sent to a nursing home and to die.

“It’s not so much that having a family member make decisions for you makes things worse,” Torke said. “It’s that people who need decision makers are sicker.”

In a commentary accompanying the new study, Drs. Yael Schenker and Amber Barnato from the University of Pittsburgh write that the frequent use of surrogate decision makers across hospital settings suggests there are ways to broaden how doctors approach these types of decisions.

“I think there are multiple ways that we can support both patient and family involvement in decision making,” Schenker, an assistant professor, told Reuters Health.

For example, she and Barnato write that doctors should ask about people’s preferences when they are admitted to the hospital. That includes asking people who they want involved in the decision making process and how they want that person involved.

Doctors should also be trained in how to facilitate discussions between themselves, the patients and their chosen surrogate, they write. Part of that may include overcoming a tendency to only consider short-term outcomes instead of a patient’s overall illness and goals.

“I think it’s always helpful for patients and families to start conversations about these things,” Schenker said. “I think it’s also important for patients when they’re hospitalized to let doctors know how they want to approach decisions. It’s also unfortunately the case that they won’t always be asked.”

In the study, the researchers found that only about 25 percent of the patients had living wills or some kind of advanced directive to explain their choices. Torke said those documents may help some people but will not cover everything a surrogate may encounter.

“For older adults and their family members, I hope people will have more conversations about the possibilities about going into the hospital and what the older people’s preferences are,” she said.

Source: Chicago tribune

Heavy drinking in middle age may speed men’s mental decline

Middle-aged men who drink heavily show declines in memory, attention and reasoning skills up to six years sooner than those drinking less alcohol, new research suggests.

European scientists found that men drinking 2.5 or more alcoholic beverages daily at midlife were more likely to experience more rapid mental losses over the next decade than light or moderate drinkers.

Heavy drinking’s effects on women could not be accurately assessed because far fewer middle-aged females participated in the research, the study authors said.

“Heavy alcohol consumption is known to be detrimental for health, so the results were not surprising . . . they just add that [it’s] also detrimental for the brain and the effects can be observed as [early] as 55 years old,” said study author Severine Sabia. “There is no need to be an alcoholic to see a detrimental effect of heavy alcohol consumption on cognition [thinking skills].”

Sabia is a research associate in the department of epidemiology and public health at University College London. The study was published online Jan. 15 in the journal Neurology.

Scant research has examined the impact of alcohol consumption on brain aging before old age, according to study documents. The new study, however, included data from more than 5,000 men and 2,000 women at midlife.

Participants’ alcohol consumption was assessed three times in the 10 years before the first of three tests of memory and executive function, which deals with attention and reasoning skills needed in achieving goals. The first test was taken when participants were an average age of 56.

No differences were found in memory and executive function decline between men who didn’t drink alcohol and those who were light or moderate drinkers, consuming up to two servings of beer, wine or liquor each day. Heavy drinkers exhibited mental declines between 1.5 and 6 years faster than those drinking less.

Although the study found an association between heavy drinking in men and earlier decline in mental function, it did not prove a cause-and-effect relationship.

“We have lots of clinical experience to suggest that heavy drinking can have adverse effects on cognition. But what was new about this study, at least in men, was that it didn’t seem that light or moderate drinking” was more harmful than not drinking alcohol at all, said Dr. Marc Gordon, chief of neurology at Zucker Hillside Hospital in Glen Oaks, N.Y., who was not involved in the research.

“A relative strength of this study was that it looked at drinking at much younger ages than waiting until participants were elderly,” added Gordon, also an Alzheimer’s disease researcher at the Feinstein Institute for Medical Research in Manhasset, N.Y. “And nothing in this study [contradicts the idea] that having one drink a day is OK.”

Sabia agreed, saying the results echo previous studies and suggest that moderate alcohol consumption is not likely to harm people’s memory and executive function.

Source: web md

 

Fish oil ‘cures’ brain damaged kid

A teenager, who had severe brain damage after a brutal hit-and-run has made miraculous recovery due to consumption of fish oil.

Grant Virgin, who suffered from a torn aorta, a traumatic brain injury, compound bone fractures and spinal fracture after being struck by a car, was told by the doctors that he wouldn’t be alive by next morning, News.com.au reported.

However, the boy’s family vowed to save their kid, who underwent multiple surgeries remained in a coma with severe brain damage, and rubbed progesterone cream on their son, and soon saw him waking up and speaking simple words and phrases.

The Virgins thought about giving their son fish oil, after learning that the brain’s cell wall is partly comprised of the same omega-3 fatty acids, and put him on a regimen of 20-gram-per-day.

The teenager is still a long way from making a full recovery, but the family claimed that he is progressing by the day.

Source: Business standard

Caffeine pill ‘could boost memory’

A US study has raised the possibility that we may one day rely on caffeine to boost memory as well as to wake up.
The research, published in Nature Neuroscience, tested the memories of 160 people over 24 hours.

It found those who took caffeine tablets, rather than dummy pills, fared better on the memory tests.

But experts warned people to remember caffeine could cause negative effects, such as jitteriness and anxiety.

The Johns Hopkins University study involved people who did not regularly eat or drink caffeinated products.

Saliva samples were taken, to check base levels of caffeine, then participants were asked to look at a series of images.

Five minutes later they were given either a 200-milligram caffeine tablet – equivalent to the caffeine in a large cup of coffee, according to the researchers – or a dummy pill.
Saliva samples were taken again one, three and 24 hours later.
The next day, both groups were also tested on their ability to recognise the previous day’s images.

Twenty-four hours may not sound like a long time, but it is in terms of memory studies. Most “forgetting” happens in the first few hours after learning something.
People were purposely shown a mixture of some of the initial tranche of images, some new – and some that were subtly different.

Being able to distinguish between similar, but not identical items, is called pattern separation and indicates a deeper level of memory retention.
More members of the caffeine group were able to correctly identify “similar” images, rather than wrongly saying they were the same.

Prof Michael Yassa, who led the study, said: “If we used a standard recognition memory task without these tricky similar items, we would have found no effect of caffeine.
“However, using these items requires the brain to make a more difficult discrimination – what we call pattern separation, which seems to be the process that is enhanced by caffeine in our case.”

Only a few previous studies have been carried out into caffeine’s effect on long-term memory, and those that have been done generally found little effect.
This study was different because people took the caffeine after, rather than before, they had seen and attempted to memorise the images.

The team now want to look at what happens in the hippocampus, the “memory centre” of the brain, so they can understand caffeine’s effect.
Moderation
But Prof Yassa said their findings do not mean people should rush out and drink lots of coffee, eat lots of chocolate – or take lots of caffeine pills.
“Everything in moderation. Our study suggests that 200mg of coffee is beneficial to those who do not regularly ingest caffeine.

If you take too much caffeine there could be negative consequences for the body”
End Quote Dr Ashok Jansari University of East London
“Keep in mind that if you’re a regular caffeine drinker this amount may change.”
He added: “There are of course health risks to be aware of.

“Caffeine can have side effects like jitteriness and anxiety in some people. The benefits have to be weighed against the risks.”

Dr Anders Sandberg from the Future of Humanity Institute at the University of Oxford, said: “The paper demonstrates that giving caffeine after seeing images does improve recognition of them 24 hours later, supporting the idea that it helps the brain consolidate the learning.

“However, there was no straight improvement in recognition memory thanks to caffeine. Rather, the effect was a small improvement in the ability to distinguish new images that looked like old, from the real old images.”

He added: “Caffeine may still be helpful for paying attention to what you are studying and hence help your encoding, but the best way of boosting consolidation is sleep – which might be a problem in this case, if you take the caffeine too close to bedtime.
Dr Ashok Jansari, from the University of East London’s school of psychology, said caffeine appeared to “sharpen” memory, rather than actually making it better.

He said: “I would definitely not advise that people start taking in as much caffeine as possible since in terms of memory anything above 200mg may not help much and if you take too much caffeine there could be negative consequences for the body.”

Source: BBC news

Brain Injuries May Raise Risk of Early Death

People who have suffered a traumatic brain injury appear to have a much higher risk of dying prematurely, a new study suggests.

These risks include having another brain injury, being assaulted and suicide. The risks are even higher for those with a psychiatric or drug abuse problem, the researchers added.

“After a traumatic brain injury, patients have a threefold increased risk of dying prematurely,” said lead researcher Dr. Seena Fazel, a Wellcome Trust senior research fellow in clinical science at the University of Oxford in England.

“Fifty percent of the early deaths are due to either accident or suicide or being assaulted,” he said. “That seems to be related to psychiatric illness and substance abuse.”

The study found that 61 percent of these patients had psychiatric or substance abuse problems, Fazel said. In some cases, these problems were present before the injury, while some developed after the injury, he added.

The dangers of developing psychiatric or drug abuse problems after an injury may be caused by a variety of factors, including biological and social changes.

These risks might be a particular problem for soldiers and athletes who have had a traumatic brain injury, Fazel suggested.

“A large number of vets have suffered traumatic brain injuries, and we know a lot of vets are dying from suicide. Traumatic brain injury may be one of the factors that increases their risk,” he said.

Fazel believes that after a traumatic brain injury, patients need to be monitored for risk factors that may put them at risk for dying prematurely.

“Some of these problems, like psychiatric illness and substance abuse, can be treated,” he said.

While the study found an association between traumatic brain injury and early death, it did not establish a cause-and-effect relationship.

The report was published online Jan. 15 in JAMA Psychiatry.

One expert said he thinks certain personality traits play a part in the phenomenon.

“The people that are dying earlier have personality characteristics that make them vulnerable to have brain injury,” said Dr. Robert Robinson, a professor of psychiatry at the University of Iowa and author of an accompanying editorial.

“These people are being injured because they’re impulsive and thrill-seeking. These vulnerable personality characteristics are getting them not only into their first head injury, but into a subsequent head injury and that’s causing this premature death,” he said.

Another expert agreed.

“It makes sense that people who suffer a brain injury are more likely to repeat behavior over time, and have more injuries and be at risk for premature death,” said Dr. Jamie Ullman, director of neurotrauma at North Shore University Hospital in Manhasset, N.Y.

“A lot has to do with behaviors that would get them involved in injuries in the first place. We need to focus on the underlying behaviors that have resulted in these injuries, and see if these behaviors can be modified after the injury,” she said.

Source: web md

Roche ‘brain shuttle’ technology offers Alzheimer’s hope

Roche logo_Reuters.jpg

Swiss drug maker Roche has found an efficient way for complex antibody drugs to reach and penetrate the brain, raising the possibility of more effective treatments for diseases such as Alzheimer’s.

The innovative brain shuttle technology, which has so far been tested in mice, can cross the blood-brain barrier that has been a key obstacle for researchers working on neurological drugs because it acts as a seal against large molecules such as antibodies.

Alzheimer’s is a fatal brain-wasting disease that affects 44 million people worldwide, with the number set to triple by 2050, campaign group Alzheimer’s Disease International says.

Although there is still no treatment that can effectively modify the disease or slow its progression, a number of companies – including Roche, Eli Lilly, Merck & Co and Johnson & Johnson – are pursuing a variety of approaches to get to the root cause.

It is proving an uphill battle. Over the past 15 years more than 100 experimental Alzheimer’s drugs have failed in tests. Industry analysts believe that the prize for a truly effective drug could be a market worth $10 billion in annual sales.

Roche’s new technology works by hijacking a natural transport mechanism called receptor-mediated transcytosis, which is normally used by the body to transfer proteins inside the brain.

“We have basically designed this module, called shuttle, that binds to this transport mechanism and shuttles a cargo inside the brain,” Luca Santarelli, Roche’s head of neuroscience, ophthalmology and rare diseases, said in a telephone interview.

ANTIBODY BOOST

Results of a study published in the journal Neuron on Wednesday found the technology helped to increase the concentration of antibodies in the brains of mice, reducing the amount of amyloid plaque, which is a hallmark of Alzheimer’s.

Roche tested a precursor of its experimental Alzheimer’s drug gantenerumab in the pre-clinical trials. The amount of antibody that penetrated the brain increased more than fiftyfold.

Santarelli said that the brain shuttle technology is not limited to the memory-robbing disease and could be applied to other neurodegenerative disorders such as Huntington’s disease. The drugmaker is in the process of evaluating which therapeutic targets and diseases to prioritize.

Roche has struck a deal with U.S. biotech firm Isis to develop treatments for Huntington’s and aims to engineer a shuttle to increase penetration of drugs into the brain. It is also working on a program with Irish company Prothena in Parkinson’s disease.

Santarelli said that all projects are still in pre-clinical testing and the company needs to undertake a few more steps before it can begin clinical trials.

Turning to Roche’s Alzheimer’s pipeline, he said that its Phase III trial of gantenerumab in patients who have yet to develop dementia is on track, with results expected in the first half of 2016.

Roche has two other drugs in clinical testing, including crenezumab, which has been chosen for a U.S. government-backed trial in a group of Colombians with a genetic mutation that leads to Alzheimer’s in their forties.

Source: health wise daily

Daily routines may influence sleep quality, quantity

Maintaining a consistent daily routine may be linked to better sleep, according to a small new study.

Young adults who went to work and ate dinner around the same time every day typically slept better and woke up fewer times during the night. They also fell asleep more quickly at bedtime.

Yet the exact time people performed daily activities—say, eating dinner at 6 p.m. versus 8 p.m. —had little bearing on how well they slept.

“For the majority of sleep outcomes, we found that completing activities at a regular time better predicted sleep outcomes than the actual time of day that activities were completed,” Natalie Dautovich, a psychologist at the University of Alabama in Tuscaloosa, said. She led the study, which was published in the Journals of Gerontology: Series B.

“For example, people reported better sleep quality and fewer awakenings at night when they were consistent in the time they first went outside,” Dautovich told Reuters Health in an email.

On the other hand, for older adults, inconsistent daily schedules were sometimes linked with better sleep, the researchers found.

For instance, older people whose dinnertime varied tended to sleep longer at night. And those who started home activities or began work at different times each day fell asleep more quickly.

The study included 50 adults between the ages of 18 and 30 and another 50 between 60 and 95. Participants kept a diary of when they performed regular activities and how well they slept at night for two weeks.

Instead of opening the door to new recommendations or sleep treatments, the authors said the study best serves to create questions for future research.

Those questions include whether older adults who have more variation in their daily schedules are already healthier and more socially active—or whether it’s the variety in one’s everyday schedule that provides the activity and stimulation that help ensure good sleep, according to Dautovich.

“We know that good sleep at night is dependent in part on our drive to sleep, which is based on how active and alert we are during the day,” she said.

For that reason, being out and about during the day remains one of the best ways to maximize the chances of a solid night of shut-eye.

“Greater activity and levels of alertness during the day increase our need to sleep at night,” Dautovich said.

Source: GMA network

Study: Concussions May Lead To Alzheimer’s Plaque Buildup For Some

Concussions have already been linked to the Alzheimer’s-like degenerative brain disease chronic traumatic encephalopathy (CTE) in athletes and military members who have experienced repeated head blows and traumatic brain injuries.

Now, a new study links concussions to Alzheimer’s disease itself.

Mayo Clinic researchers gave brain scans to 141 Minnesotans who had been experiencing memory problems, and found those who had suffered a brain injury that caused them to black-out had more amyloid plaques in their brain than those who hadn’t.

Amyloid plaque is the telltale sign of Alzheimer’s disease, formed by pieces of a sticky protein that break off in the brain and clump together. Some clumps may form in brain regions involved in learning, memory and thinking, the Alzheimer’s Association explains. More plaques form as the disease progresses.

Researchers gave brain scans to 448 people without any memory or cognitive problems, and 141 people who had mild cognitive impairment (MCI), a condition characterized by declines in memory and thinking skills that aren’t caused by aging. They were also asked whether they had ever experienced a brain injury that caused them to lose consciousness. People with MCI are at a heightened risk of developing Alzheimer’s or another type of dementia, but not everyone with the condition will get worse.

The researchers found 18 percent of those with MCI had reported a prior brain injury, and on scans, they saw the patients had an average of 18 percent more amyloid plaques than those with no history of head trauma. They found no plaque differences in any of the brain scans of people without memory problems, regardless of whether they’d had a brain injury.

Source: dig triad

Stress in job linked to later health problems

More strain at work might mean more illness in old age, according to a new study from Finland. The study found both physical and mental job strain were tied to hospital stays later in life.

Mental job strain can come from tight deadlines, high demands and having little control over one’s work. Physical strain includes sweating, breathlessness and muscle strain.

“Job strain is something that is individually perceived, so persons working in similar jobs can report different amounts of job strain,” lead researcher Mikaela von Bonsdorff said. “When talking about job strain it is important to remember that occasional feelings of job strain are not necessarily a bad thing, but persistent high job strain has been identified as a health hazard.”

Recent studies have linked long-term job strain to lower functioning that lasts into old age, added von Bonsdorff. She is a gerontology researcher at the University of Jyväskylä in Finland.

The new findings come from a study of more than 5,000 middle-aged Finnish public sector employees who were initially surveyed about stress at work in 1981.

The researchers combined that information with data from national hospital records spanning the next 28 years.

With higher strain in midlife, days in the hospital tended to increase, especially for physical strain.

For instance, for every 1,000 men with low physical job strain, about eight days were spent in inpatient hospital care every year, on average. That compared to almost 13 days for every 1,000 men with high physical job strain, according to findings published in Age and Ageing.

“What was interesting was that these associations were clear also when we looked at hospital care that took place after the individuals had turned 65, indicating that these associations were also robust in older age and not that the association was due to hospital care that took place immediately after the baseline assessment of job strain,” von Bonsdorff said.

For both men and women, hospital days increased as physical strain increased. But for mental strain, the link was only clear among men.

“Job strain of some sort can occur in basically any type of employment,” Loretta Platts told Reuters Health.

“Although physical job strain is confined to certain sorts of occupations, such as manual occupations or low-level service occupations like being an electrician, caretaker, driver, builder, cleaner, waiter, waitress, cook or shop assistant,” she said.

Platts is a doctoral candidate at Imperial College London. She studies how various factors influence quality of life after retirement and was not involved in the new research.

“The mechanism might be the development of musculoskeletal disorders from high physical strain jobs, which are often irreversible and painful, and can lead to osteoarthritis, a leading cause of hospital admissions in older people,” Platts said. “In addition, immobility can be related to weight gain, which in turn leads to heart failure, high blood pressure and diabetes.”

Mental strain has been linked to heart disease, another cause of hospital stays.

Still, the study can’t prove that job strain causes poor health and more hospital stays, Platts pointed out.

High-strain jobs might be undesirable for many people, so it’s possible people working those kinds of jobs were unable to get less stressful jobs for an unknown, but relevant, reason. That reason could also be connected to their healthcare use.

It’s also possible that 28 years later, the people spending the most time in hospitals happened to think more negatively about their work in 1981, she said.

“This study was only of public sector employees and came from a country with a very developed welfare state. The consequences for people working in the private sector and in countries with less generous welfare states are likely to be worse,” Platts said. “The public sector in Finland is probably a best-case scenario.

Source: GMA News