FDA: Aleve may be safer on heart than other drugs

Federal health officials say the pain reliever in Aleve may be safer on the heart than other popular anti-inflammatory drugs taken by millions of Americans.

A Food and Drug Administration review posted online Tuesday said naproxen — the key ingredient in Aleve and dozens of other generic pain pills — may have a lower risk of heart attack and stroke than rival medications like ibuprofen, sold as Advil and Motrin. FDA staffers recommend relabeling naproxen to emphasize its safety.

The safety review was prompted by a huge analysis published last year that looked at 350,000 patients taking various pain relievers. The findings suggest naproxen does not carry the same heart risks as other medications in the class known as nonsteroidal anti-inflammatory drugs, or NSAIDs.

The agency released its memo ahead of a public meeting next month where outside experts will discuss the new data and whether naproxen should be relabeled. The agency is not required to follow the group’s advice, though it often does.

If ultimately implemented, the labeling changes could reshape the multibillion-dollar market for drugs used to treat headaches, muscle pain and arthritis.

The change could make Aleve and other naproxen drugs the first choice for patients with a higher risk for heart problems, according to Ira Loss, a pharmaceutical analyst with Washington Analysis. But he added that all NSAIDs will continue to carry warnings about internal bleeding and ulceration, a serious side effect that is blamed for more than 200,000 hospital visits every year.

Source: nbc news


Teen fitness is linked to reduced risk of myocardial infarction

If teenage boys were asked to choose between exercising and playing computer games, the majority would choose computer games. But new research suggests adolescent boys should be more physically active, as low fitness levels may increase their risk of having a heart attack later in life.

This is according to a study published in the European Heart Journal.

A research team from Sweden, led by Prof. Peter Nordström, of Umeå University, analyzed data of 743,498 men. All men were a part of the Swedish armed forces between 1969 and 1984, and underwent a medical examination when they were 18-years-old.

The medical examination involved measuring the participants’ blood pressure, weight, height and muscle strength.

It also measured their aerobic fitness through a cycle test. Cycling resistance was increased by 25 watts a minute until the participants’ were too exhausted to carry on. Their maximum wattage was used for the study.

The research team divided the participants’ results into five groups, ranging from the lowest levels of aerobic fitness to the highest.

All men were followed for an average of 34 years until either the date of death, the date of their first heart attack, or until January 1 2011.

During the follow-up period, there were 7,575 incidences of myocardial infarctions – the equivalent to approximately 1,222 heart attacks per 100,000 men.

High aerobic fitness linked to lower heart attack risk
On comparing aerobic fitness with the participants’ risk of heart attack, the researchers found that men in the lowest aerobic fitness group were 2.1 times more likely to suffer a heart attack later in life compared with men in the highest aerobic fitness group.

The results also revealed that for every 15% increase in aerobic fitness, the men were 18% less likely to have a heart attack. This was after taking factors such as body mass index (BMI) and socioeconomic background into consideration.

Furthermore, the investigators found that men who carried out regular cardiovascular training in late adolescence reduced their risk of heart attack later in life by 35%.

Results dependent on BMI
To analyze how BMI and aerobic fitness combined had an impact on the participants’ risk of heart attack, the researchers separated the men into four groups in line with the World Health Organization’s definitions of BMI.

These were:

Underweight/lean (BMI less than 18.5kg/m2)
Normal weight (BMI between 18.5-25kg/m2)
Overweight (BMI between 25-30kg/m2)
Obese (BMI over 30kg/m2)
Results revealed that the fittest obese men had almost double the risk of heart attack compared with men who were lean but the most unfit. Furthermore, the fittest obese men had almost four times the risk of heart attack compared with the fittest lean men.

Commenting on their findings, Prof. Nordström says:

“Our findings suggest that high aerobic fitness in late adolescence may reduce the risk of heart attack later in life.

However, being very fit does not appear to fully compensate for being overweight or obese in respect to this risk. Our study suggests that it’s more important not to be overweight or obese than to be fit, but that it’s even better to be both fit and a normal weight.”

He notes that further research is needed to determine how these findings are clinically relevant, “but given the strong association that we have found,” he adds, “the low cost and easy accessibility of cardiovascular training, and the role of heart disease as a major cause of illness and death worldwide, these results are important with respect to public health.”

Source: Medical news today


Shingles dramatically increases heart disease, stroke risk

If you’ve had shingles before the age of 40, you could be at an increased risk for heart disease and stroke.

According to Counsel & Heal, researchers followed individuals for an average of 6.3 years after they had contracted shingles. The study found that participants who had shingles before age 40 were 50 percent more likely to have a heart attack than people who did not have the disease; they were also 74 percent more likely to have a stroke.

Given these findings, lead researcher Dr. Judith Breuer of University College London recommended that anyone with shingles be screened for heart and stroke risk factors.

“The shingles vaccine has been shown to reduce the number of cases of shingles by about 50 percent,” Breuer told Counsel & Heal.

Current shingles vaccination recommendations are for anyone over the age of 60. Researchers have yet to determine the role of vaccination in younger individuals, Breuer said.

Source: Fresh news US


The basic principles of healthy eating

Healthy eating is one of the most important things you can do to improve your general health.

Nutritious, balanced meals and healthy snacks may reduce your risk of heart disease and stroke by helping you increase your intake of heart-healthy nutrients, manage your weight, keep your blood pressure down, control your blood sugar levels and lower your cholesterol.

A healthy eating plan may also boost your overall feeling of well-being, giving you more energy and vitality. It may make you look better and feel good about yourself, inside and out.

How to make heart-healthy choices

With the vast array of food choices available today, it’s difficult to know where to begin. You may wish to start by aiming to include items from the four food groups: vegetables and fruit, whole-grain products, lower-fat milk products and alternatives, and lower-fat meat and alternatives. Eating Well with Canada’s Food Guide provides direction on the types and amount of food we should eat for overall health. It makes it easier than ever to plan your meals and snacks around a wide variety of delicious and heart-healthy foods.

When you’re grocery shopping, look for the Health Check symbol on food packaging, the Heart and Stroke Foundation’s food information program, based on Canada’s Food Guide. It’s your assurance that the product contributes to an overall healthy diet.

Source: Heart & stroke foundation


10 tips to manage high BP without pills

Hypertension on the high? Here are top 10 tips to get it down and keep it down.

Seven in 10 adults are at a greater risk of stroke or heart attack because their blood pressure is too high. Desk jobs, lack of exercise and eating salty fast foods have contributed to the problem, even among the young. If your level is consistently at or above 140mmHg/ 90mmHg (referred to as 140 over 90). The 140 figure is the systolic pressure — the pressure reached when the heart forces the blood around the body — and 90 is the diastolic pressure — the lowest pressure that occurs between heartbeats when the heart relaxes.

In India, experts say, the prevalence of hypertension ranges from 20-40 per cent in urban adults and 12-17 per cent among rural adults. But there’s no reason to worry. Simple measures will help to cut your risk.

1. Go for a weekly jog
Jogging for just an hour a week can increase your life expectancy by six years, according to a Copenhagen City Heart cardiovascular study of around 20,000 men and women aged from 20 to 93.

Researchers believe jogging delivers multiple health benefits, improving oxygen uptake and lowering blood pressure, as well as many more benefits. However, any physical activity can help lower blood pressure by strengthening the heart so it can pump more blood with less effort, thereby decreasing the force on the arteries. Power walking can be just as effective as jogging.

2. Enjoy yoghurt
Just one small pot a day can reduce your chances of developing high blood pressure by a third, according to a study presented at the University of Minnesota in the US. Scientists think naturally occurring calcium can make blood vessels more supple, enabling them to expand slightly and keep pressure low.

They found those who ate a 120g pot daily were 31 per cent less likely to develop high blood pressure over a 15-year period than those who did not.

3. Go bananas
Eating potassium-rich foods, such as bananas, and reducing salt intake could save thousands of lives every year, according to a new study published in the British Medical Journal online.
Potassium is an important mineral that controls the balance of fluids in the body and helps to lower blood pressure. Making sure you eat five.

4. Down with salt
Salt draws in fluid, raising the volume and pressure of blood in your arteries. But it’s not just the salt cellar you have to worry about — processed foods such as biscuits, breakfast cereals, takeaways and ready meals contain 80 per cent of the salt we consume, says the Blood Pressure Association. Check labels: more than 1.5g salt per 100g is a lot, but less than 0.3mg per 100g is a little.

5. Lose weight
Research has shown that dropping just a few kilos can have a substantial impact on your blood pressure. Excess weight makes your heart work harder and this strain can lead to high blood pressure.

6. Don’t smoke
The nicotine in cigarettes stimulates your body to produce adrenaline, making your heart beat faster and raises your blood pressure, making your heart work harder.

7. Work less
Regularly putting in 40 hours per week at the office raises your risk of hypertension by 14 per cent, the University of California, US, found.The risk rises with overtime. Compared with those who worked fewer than 40 hours a week, workers who clocked up more than 51 hours were 29 per cent more likely to have high blood pressure. Overtime makes it hard to exercise and eat healthily, say researchers. So try to down tools with enough time to relax in the evening and eat a healthy supper. Set a message on your computer as a reminder to go home.

8. Seek help for snoring
Loud, incessant snoring is a symptom of obstructive sleep apnea. And more than half of those with this have blood pressure significantly higher than expected for their age and general health.

Cutting out cigarettes and alcohol and losing weight will help.

9. Switch to decaf
Duke University Medical Center, North Carolina, US, found caffeine consumption of 500mg, roughly three cups, increased blood pressure by three points. Effects lasted until bedtime.

Scientists say that caffeine can raise blood pressure by tightening blood vessels and magnifying the effects of stress.

10. Think beetroot
A study published in the journal Hypertension found drink ing a 250ml cup of the juice can cut blood pressure readings in those with high blood pressure by around seven per cent. It’s thought the effect is produced by beetroot’s naturally high levels of nitrate. Eating other-rich foods — cab bage and spinach — might also help

Source: Viral news chart


Strict parenting may reduce teen smoking

Parents who set limits are less likely to have kids who smoke, regardless of their ethnic and racial backgrounds, according to a new U.S. study.

Researchers surveyed middle schoolers from diverse backgrounds and found those whose parents had an “authoritative” and “structured” parenting style were also more likely to be discouraged from smoking by their parents and less likely to become smokers.

“Many past studies have examined broad parenting styles, however this study looked at how specific parenting strategies may help protect youth from cigarette smoking initiation,” said Cassandra Stanton, an assistant professor in the oncology department at Georgetown University, who led the study.

“We also note that unlike many studies in the area that are conducted in largely white middle class samples, this study was conducted in an urban multi-ethnic low-income school district,” Stanton told Reuters Health.

It’s important to identify ways of helping parents prevent kids from starting to smoke, Stanton’s team writes in the Journal of Pediatric Psychology, because the majority of lifetime smokers begin before the age of 18.

Although the number of teenage smokers has declined significantly, one in three young adults reports smoking at least once in the past 30 days, according to a 2012 report by the U.S. Surgeon General.

Past research has found links between low discipline, parental disengagement and increased risk of smoking, Stanton’s team notes. Rates of smoking vary among ethnic groups, with white students smoking daily at a rate twice that of African American and Latino students. However, African Americans and Latinos experience significantly higher rates of smoking-related health complications later in life compared with whites.

To delve deeper into which parenting strategies are effective among a diverse set of families, the researchers recruited 459 eighth graders from two low-income inner-city schools in the Northeast. The students averaged 13-years-old, with 29 percent identifying themselves as Hispanic, 34 percent as African American, 17 percent as non-Hispanic white and 20 percent as other/mixed ethnicity.

The students took a comprehensive survey in class with parental consent. The survey asked about the student’s smoking history and whether the student’s parents smoked. It also asked questions about parenting styles, such as discipline and warmth, and whether the student would receive punishments and discussion of the dangers of tobacco if caught smoking.

The researchers then followed up four years later to assess whether students had smoked.

Stanton’s group found that what they called controlling parenting, which was associated with rule enforcement, curfews and set bedtimes, was more likely than a less strict, more understanding parenting style to go hand in hand with so-called anti-tobacco parenting strategies.

Those anti-tobacco strategies include punishing a child if he or she has been caught smoking and discussing with the child the motivations behind smoking and why smoking is so dangerous. Being on the receiving end of such anti-tobacco strategies was in turn linked to a lower likelihood of lifetime smoking for the student.

The association held regardless of race or ethnicity, which the researchers say should be reassuring because other cultural differences don’t seem to alter the effectiveness of this approach.

It is important for parents to take an active role in protecting their children from developing an addiction to tobacco, Stanton said.

“Setting and enforcing clear standards of behavior and actively monitoring and supervising a teen’s activities are important strategies for protecting youth from risky behavior,” she said.

“To protect youth from experimenting with tobacco and ultimately developing an addiction to tobacco, it is important to talk about the risks of tobacco, as well as set and enforce clear rules and consequences that are specific to tobacco.”

Heather Patrick at the Health Behaviors Research Branch of the National Cancer Institute, who was not involved in this study, believes structure and authority in parenting is an important tool in preventing teens from smoking. However, she cautions, “heavy-handed” parenting can often cause stress and strain in the relationship.

Patrick said smoking cessation interventions should be tailored to different groups to be more effective. “It’s helpful for intervention materials to have images that show a diversity of racial and ethnic groups,” she wrote in an email.

It’s also helpful, she said, for anti-smoking messages to provide examples, “like how to deal with cravings, how to be smoke free when all of your friends are smoking, or how to deal with conflict at home, to connect with the kinds of experiences real teen smokers face.”

Source: US web daily


High blood pressure continues to be a bigger problem in Southeastern US

 

One third of U.S. adults have high blood pressure, but in the southeastern part of the country the rate is well over half, according to a new study that finds too little is being done to reverse the problem.

The Southeast has been called the Stroke Belt because of well-known high rates of cardiovascular disease, including high blood pressure. But that knowledge has not led to changes, nor to a full understanding of the reasons for the population’s high risk, the study team reports.

“The rates have not changed,” though the U.S. has had treatment guidelines for high blood pressure since 1977, said one of the authors, Dr. Uchechukwu K. A. Sampson, an assistant professor of medicine at Vanderbilt University Medical Center in Nashville, Tennessee.

“The number of people who do not know that they have high blood pressure is the same,” he added.

High blood pressure is an established cause of death from cardiovascular disease and accounts for up to 7.5 million deaths worldwide each year, the researchers point out.

To investigate the persistently high rates of high blood pressure in the South, Sampson’s group used a large database with recent information on men and women in southern states covering the years 2002 to 2009.

They focused on 69,000 white and black adults with similarly low income and education levels – to eliminate poverty as a factor – and analyzed what other causes might be contributing to blood pressure problems.

Overall, they found that 57 percent of the study participants had high blood pressure. Blacks were nearly twice as likely as whites to be suffering from the disease, which has no symptoms of its own, but can lead to stroke or kidney damage if untreated.

But the racial difference was seen mainly among women. Fifty one percent of black and white men had high blood pressure, but the rates were 64 percent among black women and 52 percent among white women.

Obesity seemed to be a main driver of the problem, especially among whites, with the most severely obese having more than four times the risk of high blood pressure compared to normal weight men and woman.

Other factors linked to the likelihood of severe high blood pressure included high cholesterol, diabetes, a history of depression and a family history of heart disease.

The numbers Sampson’s group found have not changed from previous studies and that consistency is alarming, he said.

“Are they still the same factors people have found before?” Sampson said. “If they are, that is bad news, then that means we have not done what we should have done in the past few years.”

Of the study participants who knew they had high blood pressure, 94 percent were taking at least one blood pressure medication, which is a good thing, Sampson said. But only 30 percent were taking a diuretic medication that promotes water loss from the body. Diuretics should be one of the first-line medication options, the authors write.

Black people were twice as likely as whites to have high blood pressure without knowing it, Sampson said.

That racial difference did not change even when researchers accounted for differences in income and education, the authors write in the journal Circulation: Cardiovascular Quality and Outcomes.

All of this lines up with what doctors and researchers already knew, Sampson said.

Without specific studies, it’s hard to say why population rates have not gone down, and why so many people still do not know they have high blood pressure, and why so few are on diuretics, he said.

Women may not actually be more predisposed to high blood pressure, Sampson said, but they may be less aware of the risk than men.

Awareness efforts have historically focused on men when it comes to heart and blood pressure problems, but women are equally likely to have problems, he said.

“African American women are known to have a very high prevalence of hypertension and that its onset is significantly earlier than what is seen in white women,” Dr. John M. Flack said.

Flack is chair of the department of medicine at Wayne State University at the Detroit Medical Center in Michigan.

Source: news.nom


Anxiety linked to stroke risk

 

Men and women with severe symptoms of anxiety may have a higher risk of stroke than their more relaxed counterparts, a new study suggests.

“The greater your anxiety level, the higher your risks of having a stroke,” study co-author Dr. Maya J. Lambiase, of the University of Pittsburgh School of Medicine, told Reuters Health.

“Assessment and treatment of anxiety has the potential to not only improve overall quality of life, but may also reduce the risk of cardiovascular diseases, such as stroke, later in life,” she said in an email.

Dr. Philip Muskin, a professor of psychiatry at Columbia University Medical Center in New York emphasized that the stroke risk identified in the study among overly anxious individuals was not vastly increased.

“What it’s really saying is, you’re a little more likely to have a stroke,” said Muskin, who was not involved in the study. Still, he added, “I would like to be a little less likely (to have a stroke) in my life.”

Stroke is one of the leading causes of death in the U.S., but few studies have looked at psychosocial factors other than depression or psychological stress or distress, that may contribute to a person’s risk of stroke.

Yet, Lambiase and her colleagues point out, anxiety has been linked to increased cigarette smoking, alcohol abuse and physical inactivity – all of which are known to increase stroke risk.

To investigate the association between anxiety and stroke, the researchers analyzed data from 6,019 men and women who were enrolled in the First National Health and Nutrition Examination Survey in 1971-1975 and followed for about 16 years.

The participants were interviewed at the start of the study to determine the presence and severity of any anxiety symptoms, and stroke events were identified by examining hospital or nursing home discharge reports and death certificates.

A total of 419 strokes occurred throughout the study period, but the risk of stroke was higher among those who reported greater anxiety symptoms, including excessive feelings of worry, stress and nervousness, at the initial interview.

Overall, anxiety was linked to a 14 percent higher risk of stroke relative to participants who were not anxious, Lambiase and her co-authors report in the American Heart Association journal Stroke.

But stroke risk also appeared to rise in line with increasing severity of anxiety symptoms, the results suggest.

The link between anxiety and stroke risk remained even after the researchers took into consideration other factors that may have influenced cardiovascular health, such as alcohol use, physical activity and smoking. After those adjustments, men and women with higher levels of anxiety were 33 percent more likely to experience stroke than those with fewer anxiety symptoms.

Similarly, the link between anxiety symptoms and increased stroke risk remained when the researchers accounted for study participants’ age, gender and symptoms of depression.

The researchers didn’t analyze the reason for the connection between anxiety and stroke, but they speculate multiple factors are likely to be involved. These could include unhealthy coping behaviors people with anxiety indulge in as well as overactivation of the sympathetic nervous system, which controls fight-or-flight responses, such as the release of stress hormones.

“People with high anxiety levels are more likely to smoke and be physically inactive, possibly explaining part of the anxiety-stroke link,” Lambiase said. “Higher stress hormones, blood pressure or sympathetic output may also be factors.”

“However,” she added, “future research is needed to determine the precise mechanisms whereby greater levels of anxiety increase a person’s risk for stroke.”

Dr. Muskin acknowledged that the study findings do point to a greater risk of stroke among overly anxious people, “but there are things you can do about that,” he said.

Noting that “anxiety predicts bad health behaviors,” Dr. Muskin cited the importance of stopping smoking and starting to exercise. He also described the importance of meditation and proper breathing techniques, which he teaches in his private practice with patients.

“Doing nothing leaves you at a higher risk (of stroke),” he said, but breathing exercises have “a psychologically beneficial effect,” with no harm and no addicting qualities, he told Reuters Health.

source: yahoo news


Patient doing well with French company’s artificial heart: report

A 75-year-old Frenchman was feeding himself and chatting to his family, more than a week after becoming the first person to be fitted with an artificial heart made by French biomedical company Carmat, one of his surgeons said.

“He is awake, feeding himself and talking with his family. We are thinking of getting him up on his feet soon, probably as early as this weekend,” Professor Daniel Duveau, who saw the patient on Thursday, told Le Journal du Dimanche newspaper.

A more detailed account of the patient’s health would be made public on Monday, the paper wrote.

Heart-assistance devices have been used for decades as a temporary solution for patients awaiting transplants, but Carmat’s bioprosthetic product is designed to replace the real heart over the long run, mimicking nature using biological materials and sensors.

It aims to extend life for patients suffering from terminal heart failure who cannot hope for a heart transplant, often because they are too old and donors too scarce.

 

The artificial heart, which can beat up to five years, has been successfully tested on animals but the December 18 implant in a Paris hospital was the first in a human patient.

Three more patients in France are due to be fitted with the device. The next operation is scheduled for the first weeks of January, the newspaper reported.

In this first range of clinical trials, the success of the device will be judged on whether patients survive with the implant for at least a month.

The patients selected suffer from terminal heart failure – when the sick heart can no longer pump enough blood to sustain the body – and would otherwise have only a few days or weeks to live.

Artificial hearts thus fuel huge hope amongst patients, their families, and investors. Shares in Carmat have risen more than five-fold since floating on the Paris exchange in 2010.

Duveau told the JDD that Carmat’s first patient was very combative and confident with his new prosthetic heart.

“When his wife and his daughter leave him, he tells them: ‘See you tomorrow!’ All he wants is to enjoy life. He can’t wait to get out of the intensive care unit, out of his room, and out of uncertainty.”

Source: Fresh News


Stroke: warning signs of this silent killer

Many warning signs may indicate a stroke. Depending on the function of the part of the brain being affected, the person suffering the stroke may become paralyzed, blind or unable to speak.

if you experience any of these major stroke warning signs: act immedicately

Sudden loss of speech
Slurred speech
Sudden loss of vision
Blurry or double vision
Sudden paralysis
Sudden weakness
Sudden dizziness
Sudden, severe headache, often accompanied by neck stiffness and vomiting.

What are the first signs of a stroke?
In severe cases, a person suffering from a stroke may become paralyzed, blind or unable to speak. But in other cases, signs may be more subtle. You should act quickly… call 9-1-1 right away and get the person to an emergency department … at the first signs of a stroke.

Why is fast action so important?
For every minute brain cells are deprived of oxygen during a stroke, brain damage increases. The chances for survival and recovery improve when treatment begins within the first few hours of stroke warning signs – often when a thrombolytic agent or “clot buster” medication is given within the first three hours of the onset of stroke symptoms.

Source: Union Hospital