A new study has found that nearly half of cancers are diagnosed only when the disease is at an advanced stage, meaning treatment is both more expensive and less likely to succeed.
Cancer Research UK said that tens of thousands of patients could have their survival chances improved if doctors were able to catch cancer before it spreads around the body, adding that early detection would also save the NHS nearly 210 million pounds, the Independent reported.
Cancer Research UK’s chief executive Harpal Kumar said that their report “provides a compelling case for substantial investment in efforts to achieve earlier diagnosis” and not to invest in earlier diagnosis is to fail cancer patients.
He said that earlier diagnosis saves lives and it could save critical NHS funds. And in the face of an overstretched NHS and a projected growing number of cancers diagnosed in the years ahead, we need to do everything we can to ensure that all patients have access to the best treatment as early as possible.
Source: zee news
A new study by Indian origin researcher has revealed that the synthesis of the most active component of grape seed extract, B2G2, encourages the cell death known as apoptosis in prostate cancer cells while leaving healthy cells unharmed.
“We’ve shown similar anti-cancer activity in the past with grape seed extract (GSE), but now we know B2G2 is its most biologically active ingredient which can be synthesized in quantities that will allow us to study the detailed death mechanism in cancer cells,” Alpna Tyagi, PhD, of the University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, said.
Previous studies have shown the GSE effectiveness against cancer cells and have also shown its mechanism of action. However, Tyagi said that until recently, they didn’t know which constituent of GSE created this effect. This naturally occurring compound, GSE, is a complex mixture of polyphenols and also so far it has been unclear about the biologically active constituents of GSE against cancer cells.
Eventually the group pinpointed B2G2 as the most active compound, but, “it’s expensive and it takes a long time to isolate B2G2 from grape seed extract,” Tyagi says.
The current study reported the success of this effort, including the ability to synthesize gram-quantity of B2G2 reasonably quickly and inexpensively.
The study also showed anti-cancer activity of synthesized B2G2 similar in mechanism and degree to overall GSE effectiveness.
The study was published in the journal Nutrition and Cancer.
Source: Zee news