Lifestyle diseases affecting men in metros

jpg

Lifestyle diseases like diabetes and high cholesterol are now hitting more young men in metropolitan cities of India, says a new survey released here Monday on the occasion of World Men’s Health Week.

Of the 38,966 samples screened during June 9-15, 56.81 percent reported high diabetes levels. Over 41.48 percent of the samples were in the age group of 20-40, indicating an increasing trend of younger population getting hit by diabetes.

In another sample of 35,886 males, the survey found 8.21 percent with high cholesterol levels and 23.01 percent in the same age group with growing rate of cholesterol. The survey was conducted in Mumbai, New Delhi, Chennai and Ahmedabad by Metropolis Healthcare Ltd.

High diabetes levels are usually associated with age, but other factors like body mass index, stress, family history of the disease, lack of physical activity etc. also significantly add to the problem. Moreover, both diabetics and high-cholesterol patients are highly risk-prone to cardiovascular diseases besides other major health problems.

The study suggested that besides regular screenings, people should go for preventive measures like reducing obesity, increasing physical activity, decreasing salt intake, among others.

Source: wonder woman


Cure for lifestyle-related diseases comes closer to reality

A new research suggests that changing your lifestyle could actually help your body’s metabolism, which could help fight against major diseases.

The study has found that an unhealthy lifestyle leaves traces in the DNA, which may have specific effects on metabolism, causing organ damage or disease.

Scientists of Helmholtz Zentrum Munchen have now identified 28 DNA alterations associated with metabolic traits in the world-first epigenome-wide association study (EWAS) of modified genes and metabolites.

In the course of life, aging processes, environmental influences and lifestyle factors such as smoking or diet induce biochemical alterations to the DNA.

Frequently, these lead to DNA methylation, a process in which methyl groups are added to particular DNA segments, without changing the DNA sequence.

Such processes can influence gene function and are known as epigenetics.

Scientists of the Institute of Genetic Epidemiology (IGE) and the Research Unit Molecular Epidemiology (AME) at Helmholtz Zentrum Munchen are seeking to determine what association exists between these epigenetic processes and the health consequences, in particular for the metabolism.

To this end, the team led by Christian Gieger (IGE) and Melanie Waldenberger (AME), in collaboration with Karsten Suhre of Weill Cornell Medical College in Qatar analyzed blood samples from more than 1800 participants of the KORA study.

In doing so, they analyzed more than 457,000 loci in the DNA as to biochemical alterations and compared them with the concentrations of 649 different metabolites.

The analysis showed that the methylation of 28 DNA segments changed a number of important metabolic processes.

“This study gives us new insights into how lifestyle factors can influence metabolism via the resulting alterations in the DNA,” Gieger, research group leader at the IGE, said.

“We can now use these results to develop new diagnostic and therapeutic approaches for lifestyle-related diseases such as diabetes,” he said

The research is published in the journal Human Molecular Genetics.

Source: ANINews