Lefty or righty? Genes for handedness found

Genes that play a role in the orientation of internal organs may also affect whether someone is right- or left-handed, new research suggests.

The study, published Friday in the journal PLOS Genetics, suggests those genes may also play a role in the brain, thereby affecting people’s handedness.

Still, the findings can’t yet explain the mystery of why a minority of people are left-handed because each gene plays only a tiny role in people’s handedness.

“Handedness is a complex trait, there are hundreds of genes involved,” said study co-author William Brandler, a genetics doctoral candidate at the University of Oxford in England. “There are also lots of environmental influences.”

Origins of handedness

Throughout the world, between about 5 and 20 percent of the population is left-handed. Favoring one hand for most tasks can allow people to do things more quickly, but exactly why there’s such a strong bias toward right-handedness in humans is a mystery. Humans’ close relatives, such as chimpanzees, are equally likely to be southpaws.

A 2012 study suggested that more cooperative societies that share tools and tasks have more people with the same dominant hand. Other studies propose that being a leftie is handy in a fistfight — but only if most people are expecting a right hook.

Although a few genes have been implicated in handedness, genes are not the entire story, as identical twins often favor different hands. Some have even proposed that brain damage in utero causes brains to rewire to make people lefties.

Genetic links

To get at the genetic roots of handedness, Brandler (who is a southpaw) and his colleagues asked 728 people to move a row of 10 pegs using first their right hand, then their left. People who take much longer on one side versus the other have greater hand dominance.

The researchers then analyzed the genes of these people and identified several genes associated with greater hand dominance. They then confirmed the association in a larger group of 2,666 people.

The strongest association was with a gene called PCSK6 that creates left- and right- parts in utero. The other genes played a role in how the organs in the body are oriented.

People with defects in these genes may be otherwise healthy, but have situs inversus, a condition in which internal organs are mirrored from their normal orientation. Others have more serious defects, such as left-handed isomerism, in which people have essentially two left sides and multiple spleens throughout the body, or heterotaxia, a typically fatal condition where “organs are all over the place,” Brandler told Live Science.

The findings suggest that the same genes that affect the left-hand symmetry of organs in the body also affect the way the brain is wired. That, in turn, affects whether someone’s right or left hand is dominant.

“Handedness is an outward reflection of brain asymmetries for motor coordination,” Brandler said. “If you’re right-handed, it means you’re left hemisphere dominant for motor coordination. That’s because our brains are cross-wired.”

Still, to truly tease out the roots of left-handedness, researchers will need to untangle the role of hundreds of other genes and isolate environmental factors, he said.


8 healthy back-to-school breakfast ideas

You’ve probably heard breakfast is the most important meal of the day, but with the morning time crunch, creating a healthy family breakfast can be challenging. Research shows eating a healthy breakfast can help improve mental performance, concentration, mood, and weight maintenance. The key to a healthy breakfast is having some fiber and protein for sustained energy. Try these easy kid-friendly breakfast ideas for a back to school boost that will fuel the whole family.

Shake it up

Short on time and rushing the kids out the door? A smoothie is a kid-friendly nutritious option that can be taken to go. Almost any combo of 100 percent fruit juice, yogurt and fruit works well, along with some ice. Add in some flax seeds or chia seeds for added nutrition. On mornings when using a blender becomes too challenging, a Svelte shake makes for a tasty and healthy on-the-go breakfast option. Svelte packs 11 grams of protein and 5 grams of fiber in each eco-friendly container.

Mini bagel pizza

While you may not think of pizza as a healthy way to start the day, you can take a healthy spin on this greasy favorite for your morning meal. Top one of a whole wheat bagel with olive oil, diced tomatoes and mozzarella. Place in a broiler or toaster oven until the bagel is crispy and the cheese is melted.  Kids love the idea of pizza for breakfast, and the combination of healthy carbs and protein will keep them fueled until lunch. Pair with fresh fruit like a pear or peach for added fiber and nutrients.

Chicken wrap

There is no rule that says only breakfast foods are for breakfast. A healthy and hearty chicken wrap can be a perfect on-the-go morning choice. Wrap fresh or left over chicken with veggies in a whole grain tortilla. Add some cheese if you like for flavor and protein.

A study in the American Journal of Clinical Nutrition suggests that a high-protein breakfast may prevent unhealthy snacking later in the day. The study finds that those who incorporate protein into their morning meal are likely to feel fuller and improve their overall diet quality. If you don’t have chicken, substitute whatever protein you have on hand. Turkey, tuna, or even beans work great.

Pistachios and fruit

If you’re rushed at breakfast time, remember starting your day healthy isn’t limited to traditional breakfast foods. Try grabbing a handful of pistachios and a piece of fruit on your way out the door for a nutrient-packed way to get your day started. Sounds nuts? A small, randomized study found that eating whole nuts at breakfast kept blood sugar down and feelings of fullness up through to the second meal of the day. Up the convenience factor by packing pistachios and fruit in a bag the night before, so you can grab and go in the morning.

Breakfast taco

Breakfast tacos can be a healthy and portable morning meal for the whole family. Similar to a breakfast burrito, stuff your taco with a scrambled egg, reduced-fat cheddar cheese, salsa, and avocado for a healthy and delicious start to your day. Go for corn tortillas, which have half the calories and twice the fiber of flour tortillas. With just the right balance of carbs, protein, fat, and fiber, this powerhouse breakfast will surely keep you energized and satisfied until lunchtime.

Veggie and cheese omelet

A vegetable omelet is a quick and easy source of protein, fiber, and essential nutrients such as vitamin D. plus, packing your omelet with spinach, mushrooms and peppers is an easy way to sneak in extra veggies. A study in International Journal of Obesity reported that participants who consumed eggs for breakfast (compared to those who consumed bagels) lost more weight, had a lower BMI, and experienced a greater reduction in waist circumference. If time is really tight, wrap it in a whole-grain tortilla and take it to go.

Bar it

If you’re on the go, an energy or granola bar may seem like a “better than nothing” breakfast choice. But with literally dozens of brands to choose from in a variety of flavors, which do you, choose? Your best bet is to look for bars with “whole” ingredients (whole soy, fruit, and nuts, for example) that provide at least 3 grams of fiber and 3 grams of protein. Top choices for bars with “whole” ingredients include SoyJoy, Larabar and KIND. For a fun twist, heat a SoyJoy bar in the microwave for 20 seconds, and it tastes like a warm cookie; the banana tastes like warm banana bread.

Peanut butter and banana waffle

Kids love waffles, and now there are healthy, whole grain frozen options to make the morning rush easier. Skip the butter and maple syrup toppings and instead opt for a whole grain waffle topped with natural peanut butter (or almond butter) and banana slices. For some added sweetness, drizzle a bit of honey on top. Pair with a glass of calcium-fortified 100 percent orange juice for added nutrition, and this morning meal is sure to please.


7 tricks to improve your memory

7 tricks to improve your memory

I used to have a memory that amazed people, but in the last few years I’ve had trouble remembering names and movie titles. (“You know the one about the guy who goes somewhere? It won that award…”) I hope to have many years of sharp thinking ahead of me—I’m in my mid-40s, nowhere near senior-moments territory—so I got to wondering: Is there something I should be doing now to counteract the lapses that already seem to be taking place?

There’s no way around the fact that memory erodes as we get older. The hippocampus, the area of your brain responsible for building memory, loses 5 percent of its nerve cells with each passing decade. Plus, aging slows production of acetylcholine, a neurotransmitter vital to learning and memory. Based on these facts, scientists once believed that a person’s mental ability peaked early in adulthood, and then went downhill from there. But over the last few decades, research has found that adults’ brains are still able to form new, memory-building neural networks in a process known as neuroplasticity. The reassuring latest thinking: With a little effort, anyone can boost their power of recollection.

To test this theory in the real world, I tried an array of research-backed brain-sharpening techniques over one six-week period. Am I now able to list all 44 U.S. presidents? No. But can I more easily summon up where I put my keys? Yes. And I think being able to leave my apartment and lock the door is a more valuable life skill than remembering James K. Polk. Here’s what worked for me—and what fell flat.

Technique #1: Play brain games

Puzzles like Sudoku and crosswords may improve memory and delay brain decline, though experts are not yet sure why. “My guess is that playing them activates synapses in the whole brain, including the memory areas,” says Marcel Danesi, PhD, author of Extreme Brain Workout. Research so far is decidedly mixed: Some studies have found that, while doing crossword puzzles may make you better at remembering the capital of Burkina Faso, there’s little evidence they’ll boost your performance at more general tasks, like remembering where your car is parked. But a 2011 study showed that participants who played a computer game called Double Decision for six years improved their concentration so much that they had a 50 percent lower rate of car accidents.

So I decided to try an online brain-training program called Lumosity, which neuroscientists from Harvard, Stanford and the University of California at Berkeley have used in their own studies; its creators claim that 97 percent of users improve their memory in just 10 hours of playing time. First I answered a series of questions at lumosity.com to identify which of my cognitive processes, including memory, could use a little help. Then I received a personalized training regimen. A 10-minute daily series of games is free, and a more advanced program is available for $12.95 a month. (Being cheap, I stuck with the former.) The games are pure fun—remembering a pattern of blocks, spotting a bird in a field—and are based on what research has found to improve concentration and other cognitive skills.

My grade: B- By the end of a month, my “brain performance index” score rose 6 percent—not amazing in the Lumosity world, but respectable. The main problem: You have to play the games every day, forever, to keep up the benefits. I’ve mostly kept up. (Except on weekends. Or if I’ve had a busy week. OK, I haven’t kept up.)

Technique #2: Eat the right foods

According to Gary Small, MD, director of the UCLA Memory Clinic, memory superfoods include antioxidant-rich, colorful fruits and vegetables, which protect your brain from harmful free radicals. He’s also enthusiastic about low-glycemic carbs, like oatmeal, and anything with omega-3 fatty acids. In fact, a recent study published in Neurology found that people with low levels of omega-3s had brains that appeared to be a full two years older in MRI scans. That was incentive enough for me to follow the memory-enhancing diet from Dr. Small’s book The Memory Prescription, which claims it works in just two weeks. Much like the Mediterranean diet, it’s heavy on produce, legumes, nuts and fish. It’s low on meat, since meat’s omega-6 fatty acids may contribute to brain inflammation, a possible underlying mechanism for Alzheimer’s.

Refined sugars produce a similar effect, so they were also out. (That was the toughest for me.) I ate a farmers market’s worth of blueberries, spinach, avocado and beets, and consumed enough fish to sprout gills. I also went beyond Dr. Small’s advice and took 2.4 micrograms of vitamin B12, the standard recommended daily amount—since studies show people with low levels perform poorly on memory tests—and 1,000 international units of vitamin D, discovered by Tufts University researchers to boost cognitive function. (My doctor signed off on the supplements.)

My grade: A It was difficult to eat meat only once a week, until I noticed how much less physically and mentally sluggish I felt. And my memory became markedly sharper over 14 days. (For instance, I quit using a bookmark because I could remember the page number I’d stopped on the night before.) Planning those meals took a lot of prep, but it paid off tremendously. I still try to use the diet as a guideline: I eat meat once a week, aim for five fruits and vegetables a day and pop omega-3 supplements (since I don’t get as much fish as I did on the diet).

Technique #3: Quit multitasking

“One reason people can’t remember where their keys are is they’re not paying attention when they put them down,” says Mark McDaniel, PhD, a psychology professor and memory researcher at Washington University in St. Louis. (His suggestion for always finding them: “When you put them down, stop and say out loud, ‘I’m leaving my keys on my dresser,'” or wherever you’re placing them.) Studies show that it takes eight seconds to fully commit a piece of information to memory, so concentrating on the task at hand is crucial. I willed myself to stop giving everything “continuous partial attention,” a term coined by tech honcho Linda Stone. I put away my gadgets when they weren’t absolutely needed. I didn’t have 10 websites up all at once. I called a friend, sat on my bed, closed my eyes and actually listened to what she was saying.

My grade: B+ It’s amazing how difficult it is to do one thing at a time. Concentration takes work, but I found I could remember appointments better because I paid attention when I made them and repeated the day and time, rather than agreeing to commitments while doing the laundry and returning e-mail messages. My husband, usually my living iCal, was very impressed.

Technique #4: Master a new skill

A recent Swedish study found that adults who learned a new language showed improved memory for people’s names, among other things. Any activity that is practiced diligently, such as knitting or skiing, will likely have this effect, researchers say. I vowed to learn to play the keyboard. On YouTube I found PlayPianoKing, an affable guy who teaches everything from Pachelbel’s Canon to “Gangnam Style.”

My grade: C- While I did learn a mean “Gangnam” and felt my concentration improve, I soon gave up: With brain games and a diet overhaul crowding my schedule, the hour-long, every-other-day lesson was making me cranky, even before I saw any noticeable memory gains.

Technique #5: Get more sleep

Researchers at the University of Pennsylvania have discovered that losing half a night’s rest—three or four hours—on just one evening can erode memory. And the journal Nature Neuroscience recently reported that one way to slow decline in aging adults is to improve the length and quality of sleep. During a deep sleep of eight hours or more, it’s believed that the brain shifts memories from temporary to longer-term storage. Yet according to the Centers for Disease Control and Prevention, one third of us get less than seven hours a night—including me.

So, for more than a month, I implemented a stringent schedule: I would put my preschooler to bed and take a bath. Then I’d hit my own bed with a book, rather than watch TV or movies, which several studies reveal will make you feel too keyed up to wind down. Normally I fall asleep at 11:30 p.m. and wake at 5:45 a.m., but the new routine put me out by 10.

My grade: A+ Nothing had a better effect on my memory than that long stretch of sleep. I was able to semi-credibly measure the difference because I started my other interventions a few weeks before this one. I bounded out of bed fully recharged. My mind became as focused as a laser beam; I even remembered every mom’s name during the school run (no more “Hey, you!” or just “Hi!”).

Technique #6: Use mnemonic devices

These are basically memory tools that give meaning and organization to a random group of words or concepts. They could be an acronym (BOG for “Buy oranges and grapes”), an exaggerated visualization (imagining a massive stethoscope to remember a doctor’s appointment) or a rhyme (to recall a co-worker’s name, I’d remember, “Ted has a giant forehead”). Memory champions also love chunking, or breaking a large amount of information into more manageable nuggets. Say you have to memorize these numbers: 2214457819. It’s much easier to do as a phone number: 221-445-7819.

My grade: A+ I found these tactics enormously helpful. I usually forget my poor nephew’s birthday, but this year I actually sent a gift, thanks to the unpleasant but memorable NITS (“Nephew is 10 Sunday”).

Technique #7: Hit the gym

Researchers from the University of California at Irvine recently discovered that a little exercise might yield big mental benefits. They had one group of subjects ride stationary bikes for six minutes, while another group cooled their heels. Afterward, the active group performed significantly better on a memory test. Instant results! The researchers believe the boost may be tied to an exercise-induced brain chemical called norepinephrine, which has a strong influence on memory. And Dr. Small contends that exercise is the best memory aid of all. “It can increase your brain size,” he says—and the bigger your brain, the greater your capacity to remember. His recommendation: 20 minutes of brisk walking a day.

I began doing an hour daily—more than Dr. Small recommends, but also more consistent than the gym workouts a few times a week I used to favor, and, according to many experts, more effective in juicing up memory.

My grade: A- This moderate, regular activity worked wonders on my stress levels, and it became much easier to concentrate afterward, so I could fix things (like a grocery list) into my memory. I grew addicted to my walks and still take them. In fact, I found that the memory-boosting healthy lifestyle habits—exercising more, stressing less, eating a better diet were the most sustainable over time. And that’s a win-win.

 


Exercise may help alleviate depression, review finds

Exercise may help ease symptoms of depression, according to a fresh look at past research.

Researchers who analyzed data from previous studies found people who exercised experienced a “moderate” reduction in their depressive symptoms compared to those who did other activities, such as using relaxation techniques, or received no treatment.

“This review provides some additional evidence that there may be some benefit (to exercise),” Dr. Gillian Mead, the study’s senior author from the University of Edinburgh in Scotland, told Reuters Health.

A 2009 review from the Cochrane Collaboration, an international organization that evaluates medical research, found similar results, but more studies looking at the link between exercise and depression have since been published.

“We’d become aware of some new trials in the area and – in general – the Cochrane review should be kept updated if there is new evidence that may lead to changes,” Mead said.

About one in ten Americans reports depressed, according to the U.S. Centers for Disease Control and Prevention. The most popular treatments for depression include antidepressant medications and psychotherapy.

Mead and her fellow researchers write in The Cochrane Library, however, that many people prefer alternative treatments, and some doctors recommend exercise as a potential option.

For the new review, they searched databases for all medical trials conducted through March 2013 that compared exercise among adults with depression to other activities or no treatment.

Overall, the researchers were able to combine data from 35 trials that included 711 people who were randomly assigned to an exercise program and 642 who were randomized to comparison groups.

Because the studies used various scales to assess depression, they converted the results into a single measurement to compare people in exercise and non-exercise groups. Using that measurement, a difference between groups of 0.2 represents a small effect, 0.5 a moderate effect and 0.8 a large effect.

Mead’s team found a 0.62-point difference in depressive symptoms favoring people who exercised.

In one of the included trials from 2007, for instance, researchers found 45 percent of people who took part in supervised exercise no longer met the criteria for depression after four months, compared to 31 percent taking an inert placebo pill.

In another trial from 2002, 55 percent of older people experienced a significant decline in depression symptoms after 10 weeks of exercise, compared to 33 percent who attended informational talks during that time.

The difference between groups, however, was greatly diminished when the review authors only analyzed data from the six trials that were considered high quality.

Still, exercise appeared to reduce depressive symptoms as much as psychotherapy or antidepressant medications. But Mead cautioned that those findings are only based on data from a small number of trials.

“One has to be careful saying it was as effective as other therapies,” she said.

She added that it’s still unknown how exercise affects depression.

“There are lots of ideas about potential mechanisms, but I don’t think there is enough evidence in the literature that one mechanism applies more than another,” Mead said.

The researchers were also unable to say which type of exercise is best, but Mead said previous reviews have recommended people choose an activity that they’ll stick with over the long run.

“Once people are prescribed exercise or they choose exercise, the big challenge is to make the exercise real,” Dr. Madhukar Trivedi, who has studied the effect of exercise on depression but wasn’t involved with the new research, told Reuters Health.

“If the recommendation from the treating clinician is that you should be exercising with some frequency and intensity… it’s important that the patient follow that regimen week after week,” Trivedi, a professor of psychiatry at the UT Southwestern Medical Center in Dallas, said.

Michel Lucas, who was also not involved with the new review but has studied the topic before, said studies tend to show a dose-response relationship between exercise and depression.

“The dose is very important. If you’re walking at a very slow pace, this has no effect,” Lucas, a visiting scientist at the Harvard School of Public Health in Boston, told Reuters Health.

Source: Fox news


Nuclear plants don’t raise child leukemia risk

Despite fears to the contrary, children who live near nuclear power plants have no greater risk of developing leukemia or a type of cancer known as non-Hodgkin lymphoma, according to a large British study published on Friday.

Researchers who studied some 10,000 children aged fewer than 5 and analyzed birth records for nearly every case of childhood leukemia in Britain from 1962 to 2007 found no apparent extra risk from living near an atomic power station.

John Bithell of the Childhood Cancer Research Group, who led the study, noted there have been concerns about child leukemia near nuclear plants in Britain since the 1980s, when a television program reported an excess of cancer in children near the Sellafield plant in north-west England.

There have since been conflicting reports in Britain and other European countries about whether children living near such reactors are at greater risk of developing childhood cancers.

A study on Germany, published in 2007, did find a significantly increased risk. But a 35-year-long survey in Britain by the Committee on the Medical Aspects of Radiation in the Environment, published in 2001, found no evidence that living near nuclear plants increased the incidence of children developing leukemia.

Bithell said the findings of his research, published in the British Journal of Cancer, and should be reassure the public.

“Our case-control study has considered the birth records for nearly every case of childhood leukemia born in Britain and, reassuringly, has found no such correlation with proximity to nuclear power plants,” he said in a statement.

Leukemia is a cancer of immature white blood cells that mostly occurs in children between 2 and 4 years old.

It is rare, affecting around 500 children a year in Britain, and experts say 85 to 90 percent can now be cured.

Bithell’s research group was funded by the Scottish and English governments and the charity Children with Cancer UK.

They measured the distance children lived from the nearest nuclear plant both at birth and when diagnosed with leukemia or non-Hodgkin lymphoma.

Data on cancer cases came from the National Registry of Childhood Tumours, which has kept records of nearly all children diagnosed since 1962 and is estimated to be more than 99 percent complete for leukemia cases over the period studied.

Hazel Nunn, head of health information at the charity Cancer Research UK, said the results were “heartening”.

“This study supports the findings of the Committee on Medical Aspects of Radiation in the Environment that being born or living near a nuclear power station doesn’t lead to more cases of leukemia and similar cancers in children under 5 in the UK,” she said.

“But these results can’t rule out any possible risk, so it’s still important that we continue to monitor both radiation levels near nuclear power plants and rates of cancer among people who live close by.”

Source: fox news


10 ways to prevent bloating

The reason for your puffy belly may be bloat, not fat. In fact, one of the worst culprits for this problem—a slow digestive system—is common among women over age 40

Nothing’s more frustrating than grabbing your favorite jeans and—eek!—they aren’t even close to buttoning. But don’t despair: The reason for your puffy belly may be bloat, not fat. In fact, one of the worst culprits for this problem—a slow digestive system—is common among women over age 40. The good news is that there are lots of simple tweaks that can counteract common bloat-inducers. Here’s how to slim your silhouette.

Start off with fiber

There’s nothing distends a belly like constipation, so start your morning with a breakfast cereal packed with fiber to get things moving. Look for a cereal with both insoluble fiber (from bran) and gel-like soluble fiber (from psyllium).

Slim your veggies

Instead of noshing on raw vegetables, opt for steamed ones instead. A half-cup serving of cooked carrots delivers the same nutrition as one cup raw, but it takes up less belt-bloating room in your GI tract.

Hold the hot stuff

Give dishes a flavor boost with in-season fresh or dried herbs like dill, basil, mint, sage, tarragon, and rosemary—instead of super-spicy additions like black pepper, Chili powder, hot sauces, and vinegar. Spicy foods can stimulate the release of stomach acid, which can cause irritation.

Spit out the gum

When you chew gum, you swallow air. All that air gets trapped in your gut and causes pressure, bloating, and belly expansion.

Skip fake sugars

Sorbitol, xylitol, and mannitol are bloat-inducing sugar alcohols found in diet sodas and sugar-free gum. Avoid them for a slimmer silhouette.

Cut the carbs

As a backup energy source, your muscles store a type of carbohydrate called glycogen—and each gram of glycogen is stored with about three grams of water. But most people don’t need all this stockpiled fuel. Decreasing high-carb foods like bagels, pasta, and pretzels will help drain off excess stored fluids.

Be smart about beans

There’s a reason they’re called the magical fruit. Legumes and veggies like cabbage and Brussels sprouts induce more gas in your GI tract and can make you look like you swallowed a balloon. Soak dried beans overnight or take the OTC enzyme Beano.

Get a move on

Moving your body helps release air that has been trapped in your GI tract, relieving pressure and—you guessed it—bloating. Increasing your heart rate and breathing stimulates the natural contractions of the intestinal muscles, helping to prevent constipation and gas buildup by expediting digestion. Walk for at least five minutes to help get things moving inside your belly.

Guzzle more liquids

It seems counterintuitive—you’d think more liquid would equal more puff, right?—but getting rid of bloat means being well hydrated, so aim for at least eight glasses of water each day. Instead of plain water, try our Sassy Water that has ginger in it to help soothe your GI tract.

Avoid acidic sips

Coffee, tea, juice, and alcohol are all high-acid beverages that can irritate your GI tract, causing swelling

Bring on the bananas

Foods such as bananas, potatoes, and spinach help your body get rid of excess water weight, minimizing your middle. Extra fluid tends to accumulate when your potassium and sodium levels are out of balance. Increasing your potassium intake can bring lower your sodium.

Source : fox news


Johnson & Johnson recalls schizophrenia drug

Johnson & Johnson is voluntarily recalling one lot of schizophrenia drug Risperdal Consta after discovering mold during a routine testing process, a company spokeswoman said, and the latest in a string of recalls over the past two years.

Risperdal Consta is manufactured by Janssen Pharmaceuticals, a unit of Johnson & Johnson. The company is recalling the drug from wholesalers, distributors, pharmacies and healthcare providers.

The medicine is a long-acting form of J&J’s Risperdal anti-psychotic medication, and is used to treat bipolar disorder and schizophrenia. It is injected, unlike basic Risperdal, which is a pill.

“We estimate that fewer than 5,000 dose packs remain in the market considering our current inventory levels and the usage of this product,” spokeswoman Robyn Reed Frenze said in an email to Reuters. A single lot of Risperdal Consta consists about 70,000 dosage packs.

Frenze said that the risk to patients is considered low, and “there have been no trends of adverse events of infection associated with this lot”.

The spokeswoman added that the medication is administered to patients by healthcare professionals only, “and it is important that patients continue their prescribed treatment”.

In the past two years J&J has recalled over-the-counter drugs, contact lenses, heart devices, and insulin pump cartridges.

Source: Fox news


Obesity tied to semi-frequent migraines

everyone should be aware that obesity is associated with an increased risk of episodic migraine and not wait until a patient has chronic migraine

Overweight and obese people are at higher-than-average risk of migraines, suggests a new study.

Researchers looking at so-called episodic migraines – headaches that occur less than every other day – found they were almost twice as common among obese people as among normal-weight adults.

“This suggests patients and doctors need to be aware that obesity is associated with an increased risk of episodic migraine and not wait until a patient has chronic migraine to address healthy lifestyle choices, such as diet and exercise, and to choose medications that impact weight with care,” lead researcher Dr. Lee Peterlin, from Johns Hopkins University School of Medicine in Baltimore, told Reuters Health in an email.

However, the researchers couldn’t be sure which came first – the extra weight or the headaches. And one migraine researcher not involved in the study said he would be cautious interpreting its findings.

“If this helps of course to make people believe they should lose weight, that’s great, but does it mean that reduction in weight will reduce migraine attacks, or treat migraines? That’s a question they haven’t addressed,” Dr. Tobias Kurth, of the French national research institute INSERM and the University of Bordeaux, said.

About 10 to 15 percent of people have episodic migraines, according to Peterlin.

Previous studies have linked obesity to chronic migraines, which by definition occur at least every other day. But there’s less evidence on whether weight also plays a role in less frequent migraines, researchers said.

To try to answer that question, Peterlin and her colleagues analyzed data on 3,862 people who participated in a national U.S. survey in the early 2000s, including 188 who reported having migraines an average of three or four times each month.

About 32 percent of people with episodic migraines were obese, based on their self-reported height and weight, compared to 26 percent of non-migraine sufferers.

After accounting for other differences between people with and without migraines, such as their age and smoking rates, the researchers found that being obese was linked to an 81 percent higher chance of having episodic migraines, they reported Wednesday in Neurology.

The obesity-migraine link was stronger among women and people under 50 years old but less clear for men and older adults, who have lower migraine rates in general.

Peterlin said there are a few possible explanations for the association, including that the same systems in the body that are activated during a migraine help regulate how much people eat. Also, people who get regular migraines may be less active because of the pain or take medications that influence weight gain, she said.

Kurth, who wasn’t involved in the new study, agreed lifestyle factors may play a role in both obesity and migraines. But he cautioned against drawing a direct link between weight and episodic migraines in the absence of more research.

“I’m just very careful, because I’m missing the big picture,” he told Reuters Health.

“If obesity would cause migraine, which is the suggestion of this study, we would expect to see an increase … in the prevalence of migraine, because we have such an epidemic of obesity in the United States,” he said. “And this is just not true.”

However, Peterlin said, rates of the two conditions wouldn’t necessarily be expected to go hand and hand on a larger scale – and that some studies have suggested episodic migraines are in fact becoming more common.

Source: fox news

 


Lobsters may be the answer to immortality

Scientists say they may have found the key to eternal life in an unexpected creature – lobsters.

Research shows the crustaceans possess an enzyme called telomerase, which makes them ‘biologically immortal.’ Growing older doesn’t raise their chance of death, The Sun reported.

In other living creatures, strands of DNA get shorter as cells replicate and die, and they eventually become too badly damaged to copy new cells.

But in lobsters, telomerase prevents DNA strands from shortening, allowing perfect cells to replicate again and again, according to biologist Simon Watts, founder of ReadySteadyScience.com.

The average lobster weighs under 2 pounds, but near the coast of Maine in 2009, fishermen caught a lobster that weighed 19 pounds, meaning the creature was approximately 140 years old.

Medical experts hope further studies about telomerase will help discover new ways to increase lifespan and prevent cancer.
Source: Fox news

 


Measles still poses threat to US, health officials warn

Private school children at greatest risk of measles says leading doctor

Private school pupils ‘at greatest measles risk’

Although measles was officially “eliminated” in the United States in 2000, public health officials warned Thursday that the highly contagious, and sometimes deadly, virus continues to be imported from Europe and other parts of the world where the disease is still common. Despite high vaccination rates nationwide, measles continues to cause outbreaks in individual communities with large numbers of unvaccinated persons.

Between January 1 and August 24 of this year, the Centers for Disease Control and Prevention (CDC) received reports of 159 laboratory-confirmed measles cases. Federal health officials say all of the U.S. cases so far this year involve persons who either acquired the virus while traveling outside the U.S. or were exposed to an infected international traveler.

According to the CDC, at least 82 percent of the cases involved patients who had not been vaccinated. An additional 9 percent of the patients had unknown vaccination statuses.

Of the patients who had not received measles immunizations, 79 percent had philosophical objections to vaccination, federal health officials said.

Results of a National Immunization Survey released today show that 90.8 percent of U.S. toddlers between the ages of 19 and 35 months have received at least one dose of the measles, mumps and rubella vaccine (MMR) – just above the federal government’s target of 90 percent. However, federal health officials warned that measles imported from other countries can still cause large outbreaks in the U.S., especially if introduced into areas with clusters of unvaccinated persons.

Such clusters can exist in homes, neighborhoods, schools or religious organizations, with heavy concentrations of people who are opposed to vaccination.

Such was the case in New York City back in March. An unvaccinated 17-year-old infected with measles returned from a trip to the United Kingdom and is suspected to be the source of the largest U.S. outbreak of the disease since 1996. Public health officials identified 58 measles cases in two Brooklyn neighborhoods, all involving people who had not been vaccinated.

Fortunately none of the U.S. cases this year has resulted in death, and CDC officials said all of the outbreaks of 2013 have been contained, thanks to high vaccination rates and rapid response by public health agencies. However, they continue to urge Americans to get vaccinated because the disease is easily transmitted.

“You can bring measles virus into an arena, and anyone who’s not vaccinated in that arena who’s never had measles is going to get that virus,” said Dr. Anne Schuchat, director of the CDC’s National Center for Immunization and Respiratory Diseases.

Since elimination in 2000, the largest number of U.S. measles cases was reported in 2011, with 220 people becoming ill.

Source: Fox news