New method for stimulating ovulation may make IVF safer, study says

New method for stimulating ovulation may make IVF safer study says

British scientists have observed a new process of stimulating ovulation that may possibly offer a safer and much more helpful solution for women going through in vitro fertilization (IVF).

In a new review revealed in the Journal of Scientific Investigation, researchers discovered that the hormone kisspeptin can be applied to induce ovulation in IVF treatment method, with out the facet results of currently made use of procedures.

Ordinarily, medical practitioners use HCG, which is also a in a natural way transpiring hormone, to stimulate ovulation throughout IVF. On the other hand, mainly because the hormone immediately targets the ovaries, use of HCG places females at risk for ovarian hyperstimulation syndrome (OHSS) and perhaps lifestyle-threatening aspect outcomes. OHSS can lead to agonizing and swollen ovaries and side outcomes can involve vomiting, rapid fat obtain and kidney failure.

“One of the major difficulties in IVF is excessive stimulation of ovaries,” review author Waljit Dhillo, a professor in endocrinology and metabolism at Imperial Higher education London, informed “Each calendar year, balanced gals finish up in the clinic and there are a quantity of deaths each yr.”

Researchers at Imperial Faculty London and Imperial College Healthcare NHS Believe in in London examined a team of fifty three ladies, just about every of whom underwent a solitary injection of kisspeptin to induce ovulation. Experienced eggs made in 51 out of 53 contributors and 49 women of all ages had just one or two fertilized embryos transferred to the uterus.

From that team, twelve balanced babies were being born, which researchers deemed to be a excellent outcome when compared to standard IVF therapy.

Key infertility— when a pair has been unable to conceive for at minimum a single year— influences about million people in the United States. In accordance to the Culture for Assisted Reproductive Technology, medical practitioners executed more than one hundred sixty five,172 IVF methods in 2012.

Kisspeptin is a hormone ordinarily present in the overall body and is identified to enjoy a crucial job in puberty and reproduction. It works to market copy by triggering the release of woman sex hormones and stimulating egg development. Large concentrations of kisspeptin are generally present in a healthy pregnancy, so researchers had little problem about the hormone on fetus progress, Dhillo stated.

Scientists mentioned that a profit of utilizing kisspeptin in its place of the typical HCG hormone is that kisspeptin does not specifically goal the ovaries, even though HCG does. Also, they did not notice any unfavorable side outcomes amid participants.

“If you give HCG, the hormone goes straight to the ovary and does its work. But there is no regulation,” Dhillo mentioned. “So the similar dose can have different effects for the reason that some girls may be a lot more sensitive to it.”

Dhillo and his group now approach to check the success of kisspeptin in females with polycystic ovarian syndrome (PCOS), a subpopulation in particular vulnerable to OHSS.

Source: daily news

Suffering from Polycystic Ovarian Syndrome (PCOS)? Don’t lose hope

Suffering from Polycystic Ovarian Syndrome Don't lose hope

Are you experiencing irregular periods, weight gain, hair growth on the body and face, thinning of the hair on the head? Don’t ignore the symptoms as chances are you may be suffering from a condition called Polycystic Ovarian Syndrome (PCOS).

What is PCOS?

PCOS is an endocrine disorder which is associated with an excess of androgens or male hormones in the body. It leads to the formation of small cysts in the ovaries. According to experts, nearly 40% percent of teenagers today suffer from PCOS due to sedentary life or consumption of high calorie, high carb diet.

It is more commonly found in women living in urban areas than women residing in rural places as it is majorly a lifestyle disease. The exact cause of the disease is not known.

Symptoms of PCOS

Symptoms of PCOS include irregular, missed or scanty menstruation cycle, weight gain, excessive hair growth on chin, lower abdomen, thighs, facial hair and thinning of hair on your head.

Why worry if you have PCOS?

One of the major effect that PCOS have on a female body is that it leads to imbalance of hormones which may again interfere with the growth and release of eggs from the ovaries, thereby preventing ovulation and may lead to infertility in some cases.

Also, since the body becomes resistant to insulin, a women is at risk of obesity, hypertension, cholesterol and uterine cancer.

Is it possible to have a baby with PCOS?

The good news is that one need not be depressed as PCOS can be managed with medicines to some extent. A women can easily conceive by adopting a healthy lifestyle, eating right and maintaining healthy weight.

Treatment of PCOS

Treatment of PCOS depends partially on the woman’s stage of life. For younger women, treatments can include inducing exercises in daily routine, diet modifications and medication. Experts also prescribe the usage of birth control pills to control the menstrual cycle thereby decreasing androgen levels in the female body.

Some other treatments like Progesterone therapy is also adviced by doctors.

Source: zee news

Woman’s IVF Prevented Fatal Brain Disorder in Her Children

A woman whose genes put her at high risk for a rare brain disorder was able to avoid passing on the condition to her children through a special in-vitro fertilization (IVF) procedure, according to a new report of the case.

The woman, a 27-year-old in the United States, had undergone genetic testing that showed she had inherited a gene that put her at risk for Gerstmann-Straussler-Scheinker (GSS) syndrome, a rare and fatal brain disorder seen in only a few families in the world. Symptoms of the condition usually appear between ages 35 and 55, and include progressively worsening speech, movement and memory problems.

To have children, the woman and her husband used IVF, an assisted-reproduction technique in which eggs from the mother are fertilized in a laboratory. But before implanting the embryos in the uterus, doctors took an extra step and screened the embryos for the GSS genetic mutation.

Source: Live science

Woman Gets Pregnant Thanks to Yolk from a Hen’s Egg

A British couple who spent £40,000 and went through 12 IVF cycles trying to get pregnant have found success with an unusual treatment involving egg yolks.

Mark and Suzanne Harper agreed to the procedure after doctors revealed Suzanne had high levels of natural “killer cells” in her body that were attacking her embryos and preventing her from getting pregnant. The rare technique involved treatment with intralipid infusion – a special drip mixture that includes yolk from a hen’s egg and soy oil. The fatty acids of this combination were thought to control the aggressive cells – and it worked.

The Harpers were surprised by the main ingredient. Suzanne reveals:We were very surprised when we were told what the treatment consisted of. You don’t expect to be treated using yolk from a hen’s egg. But we were willing to try anything to try to have a baby.

Suzanne was one of the first women in Britain to undergo the pioneering treatment. When the couple decided to conceive again, they used the yolk combination along with IVF and had their second daughter. She said:

We are so happy to be parents at last — and it’s all thanks to egg yolk. It has given us both our daughters and we can’t be grateful enough.

Source: celeb baby