One Week of Junk Food May Be Enough to Damage Your Memory

 

Everyone knows that junk food is bad for the waistline, but new research suggests it can damage memory, too.
Australian researchers found that even a short term diet of junk food can have a detrimental effect on the brain’s cognitive ability.
The study suggests that obesity can trigger rapid changes in the brain.

Scientists from the University of New South Wales (UNSW) showed for the first time that rats fed a diet high in fat and sugar had impaired memory after just a week.

Interestingly, the results were similarly poor for the rats fed a healthy diet that had been given sugar water to drink, according to the study, which was published in the journal Brain, Behaviour and Immunity.

The animals found it more difficult to recognise specific places after their junk food diet and showed a lesser ability to notice when an object shifted to a new location.
The mice also had inflammation of the hippocampal region of the brain, which is associated with spatial memory.

‘We know that obesity causes inflammation in the body, but we didn’t realise until recently that it also causes changes in the brain,’ said Professor Margaret Morris from UNSW Medicine, who co-authored the study.

‘What is so surprising about this research is the speed with which the deterioration of the cognition occurred,’ she said.
‘Our preliminary data also suggests that the damage is not reversed when the rats are switched back to a healthy diet, which is very concerning.’

Some aspects of the animals’ memories were spared, regardless of their diets.
All the animals were equally able to recognise objects after eating either the healthy, healthy with sugar or ‘cafeteria’ diets, the latter of which was high in fat and sugar, including cake, chips and biscuits.
The change in the animals’ memory appeared even before the mice eating junk food gained any weight.
Ongoing work will attempt to establish how to stop the inflammation in the brain of animals with the unhealthy diets, which could unlock secrets relating to humans who eat unhealthily.
‘We suspect that these findings may be relevant to people,’ said Professor Morris.
‘While nutrition affects the brain at every age, it is critical as we get older and may be important in preventing cognitive decline. An elderly person with poor diet may be more likely to have problems.’

The research builds on previous work that has implications for obesity.
‘Given that high energy foods can impair the function of the hippocampus, if you eat a lot of them it may contribute to weight gain, by interfering with your episodic memory,’ Professor Morris said.
‘People might be less aware of their internal cues like hunger pangs and knowing when they have had enough,’ she said.

Source: mail online


Researchers Turn To Bears To Understand Obesity:


Although obesity statistics have somewhat leveled off in recent years, the global burden of this epidemic continues to rear its ugly head at adults and children. Scientists at the U.S. drug maker Amgen Inc. are experimenting with an unorthodox new study method that implores the help of an animal with one of nature’s biggest appetites: the grizzly bear. After watching Yogi Bear on TV, Dr. Kevin Corbit decided to uncover how the chubby cartoon character stayed healthy while gorging on food in preparation for hibernation.

The Washington State University Bear Center was established 27 years ago and served as one of the world’s only research facilities where grizzly bears can be thoroughly examined. Bears are either born at the university or taken from national parks where they were in danger of being euthanized due to close contact with humans. A research team headed up by Dr. Corbit is in the middle of two-year study in which they are drawing blood, running biopsies for fat deposit, and monitoring the heart of 12 grizzly bears.

Dr. Corbit and his colleagues were particularly interested in how a grizzly bear’s cholesterol and blood pressure spikes after they take in upward of 100 lbs. of fruit, nuts, and salmon, yet somehow remain healthy. Not only do grizzly bears lose this weight rapidly after hibernation, but they are also unaffected by the health conditions most obese humans experience such as a heart attack, stroke, or diabetes.

Findings revealed that each bear was able to adjust their hormone insulin sensitivity, which controls the amount of fat and sugars that are broken down and stored away for energy during hibernation. Grizzly bears experience high insulin sensitivity while preparing for hibernation; however, a few weeks into hibernation they completely shut off their insulin sensitivity. Dr. Corbit told The Wall Street Journal that sequencing the bear’s genome “would really accelerate the discovery research for bears.”

According to the World Health Organization (WHO), obesity on a worldwide scale has doubled since 1980. Over 200 million men and 300 million women over the age of 20 were considered obese in 2008. Around 2.8 million adults die each year as the result of an obesity-related condition, making it the fifth leading cause of death around the world. Forty-four percent of obese people also develop diabetes, 23 percent suffer from heart disease, and between seven percent and 41 percent are affected by a certain type of cancer.

Source: medical daily


Stressed parents make for obese kids

Researchers including an Indian-origin scientist have linked parental stress to weight gain in children.

The study found that children whose parents have high levels of stress have a Body Mass Index, or BMI, about 2 per cent higher than those whose parents have low levels of stress.

Children with higher parental stress also gained weight at a 7 per cent higher rate during the study period than other children.

Those figures may sound low, said lead author Dr. Ketan Shankardass, but they’re significant because they are happening in children, whose bodies and eating and exercise habits are still developing. Plus, if that weight gain continues and is compounded over a lifetime, it could lead to serious obesity and health issues.

Dr. Shankardass, a social epidemiologist with the hospital’s Centre for Research on Inner City Health, studied data collected during the Children’s Health Study, one of the largest and most comprehensive investigations into the long-term effects of air pollution on the respiratory health of children.

The childrens’ BMI was calculated each year. Their parents were given a questionnaire to measure their perceived psychological stress that asked how often in the last month they were able or unable to control important things in their life and whether things were going their way or their difficulties were piling up so high they could not overcome them.

Dr. Shankardass noted that more than half the students followed in the California study were Hispanic, and that the effects of stress on their BMI was greater than children of other ethnic backgrounds.

The research has been published in the journal Pediatric Obesity.

Source: top news


Sleep disturbances linked to poor quality of life in obese

A new research has showed that poor sleep quality is strongly associated with mood disturbance and lower quality of life among people with extreme obesity.

Results show that 74.8 percent of participants were poor sleepers, and their mean self-reported sleep duration was only six hours and 20 minutes.

Fifty-two percent of study subjects were anxious, and 43 percent were depressed. After controlling for age, sex, hypertension, diabetes, and obstructive sleep apnea, sleep quality and daytime sleepiness were significantly associated with mood disturbance and quality of life impairment.

“There was a clear association between the sleep problems such as short sleep duration and the psychological disorders and with quality of life,” Dr. G. Neil Thomas, from the University of Birmingham in the United Kingdom, said. “These associations remained significant even after adjusting for a range of potential confounders.

According to the authors, the potential role of sleep in the health and well-being of individuals with severe obesity is underappreciated. The results suggested that the early detection of disturbed sleep could prevent the potential development and perpetuation of psychological problems among people with extreme obesity.

The study was published in the journal Sleep.
Source: dna India


Radiographic imaging exposes relationship between obesity and cancer

Researchers at the National Institute for Aging are working to improve understanding about obesity and cancer. A study, published today in the journal Applied Physiology, Nutrition, and Metabolism, is the first to use direct radiographic imaging of adipose tissue rather than estimates like body mass index (BMI) or waist circumference, and focuses on the relationship between obesity and cancer risk in aging populations. Findings emphasize the negative impact of adiposity on long term health particularly for older men and women.

The researchers investigated relationships between fat mass and risk of developing cancer in 2,519 older adults in the Health, Aging, and Body Composition Study, a prospective, population-based study supported by the National Institute on Aging. They measured total body fat and body fat within the abdomen and thigh including visceral fat (adipose around the internal organs) and subcutaneous fat with radiographic images. Individuals were followed for cancer incidence over 13 years.

According to the study, “results suggest that adiposity may carry risk for cancers beyond those identified as obesity-related by the National Cancer Institute and further suggest a possible sex differential with respect to adipose and cancer risk.”

Dr. Rachel Murphy, lead author on the study, is a researcher at the Laboratory of Epidemiology, and Population Sciences, Intramural Research Program, National Institute on Aging, in Bethesda, Maryland.
She said, “I think it’s important to realize that BMI is not the only indicator of health to concentrate on. After controlling for risk factors we found that greater fat confers risk for cancer in older men and women. For example, women with more overall fat mass and more visceral fat had a higher risk of developing cancer.”

“For men, greater visceral adipose was a particularly strong risk factor for many types of cancer regardless of the individual’s BMI. Men with the most visceral fat had a nearly 3 times higher risk of many types of cancer (esophagus, pancreas, colon and rectum, kidney, thyroid, and gallbladder) compared to men with little visceral fat. When we controlled for BMI, the risk for visceral fat was strengthened.”

“These findings provide new insight into obesity and cancer in old age, and suggest that interventions to target visceral adipose in addition to promotion of healthy body weight may impact future cancer risk.”

Source: Medical express


Skipping meals can lead to weight gain, diabetes

Are you skipping your meals as part of a quick fix diet plan to lose weight? You are in for trouble. Because skipping meals does more bad than good to your body. Not only is your body deprived of essential nutrients but this also drastically affects the metabolism leading to weight gain and diabetes.

Most people tend to skip breakfast for instant weight loss. But in their desperate attempt they send their metabolism for a toss. Metabolism is the simple process of breaking your food into smaller, usable parts that helps you stay active through the day.  When you skip meals your metabolism has nothing to do. As a result your metabolism is unable to break down portions that you eat later in the day, and the food gets stored as fat leading to weight gain.

Skipping meals also drastically affects blood sugar levels. During metabolism some part of this food that you eat is stored as fat, while other parts enter the bloodstream as sugar, to provide you with energy throughout the day. Not eating at regular intervals can drastically lower your blood sugar levels making you susceptible to developing diabetes later in life.

So eat at the right times, eat healthy and exercise to stay fit.

Source: Zee news


Obesity Linked With Hearing Loss

Obesity is associated with a higher risk for hearing loss, according to a new study in the American Journal of Medicine.

 On the other hand, greater levels of physical activity are associated with a lower risk for hearing loss, found researchers from Brigham and Women’s Hospital.

“We often think of hearing loss as an inevitable part of the aging process, but these findings provide evidence that potentially modifiable risk factors, such as maintaining a healthy weight and staying physically active, may help in the prevention of hearing loss or delay its progression,” study researcher Sharon Curhan, M.D., Sc.M., of the Channing Division of Network Medicine at Brigham and Women’s Hospital, said in a statement.

More than 68,000 women who were part of the Nurses’ Health Study II were included in the study; their physical activity, body mass index, waist circumference and hearing loss were tracked from 1989 and 2009.

Researchers found associations between higher body mass index and waist circumference and hearing loss. Specifically, women who had a body mass index of 30 to 34 (indicative of obesity) had a 17 percent higher risk of hearing loss, compared with women who had a BMI lower than 25 (normal weight is indicated by a BMI of 18.5 to 24.9, while overweight is indicated by a BMI of 25 to 29.9). And people with a BMI of 40 or greater had a 25 percent higher risk of hearing loss.

Women with a waist circumference of 80 to 88 centimeters had an 11 percent higher risk of hearing loss compared with women with a waist circumference less than 71 centimeters. And women with a waist circumference greater than 88 centimeters had a 27 percent higher risk of hearing loss.

Meanwhile, exercise seemed to decrease risk for hearing loss. Women who were the most physically active in the study had a 17 percent lower risk of hearing loss than women who were the least physically active. And it didn’t even have to be especially strenuous activity: Researchers found that walking just two hours or more a week lowered hearing loss risk 15 percent more than walking less than an hour a week.

While the study only showed an association between hearing loss and obesity, this isn’t the first time the two have been linked. A study published earlier this year in the journal The Laryngoscope showed that obese teens have a nearly doubled risk of one-sided low-frequency hearing loss, compared to their peers of normal weight. The researchers of that study speculated that a potential reason for this association is inflammation from obesity; other potential reasons include Type 2 diabetes or heart disease from obesity, which could then lead to hearing loss.

Source: Huffington post


Sugary drinks may up uterine cancer risk

Postmenopausal women who consume sugar-sweetened drinks are at a higher risk of developing cancer of the endometrium – the lining of the uterus – a new study has warned.

Researchers found that postmenopausal women who reported the highest intake of sugar-sweetened beverages had a 78 per cent increased risk for estrogen-dependent type I endometrial cancer (the most common type of this disease).

This association was found in a dose-dependent manner: the more sugar-sweetened beverages a woman drank, the higher her risk.

“Although ours is the first study to show this relationship, it is not surprising to see that women who drank more sugar-sweetened beverages had a higher risk of estrogen-dependent type I endometrial cancer but not estrogen-independent type II endometrial cancer,” said researcher Maki Inoue-Choi.

“Other studies have shown increasing consumption of sugar-sweetened beverages has parallelled the increase in obesity,” said Inoue-Choi, who led the study as a research associate in the Division of Epidemiology and Community Health of the University of Minnesota School of Public Health.

“Obese women tend to have higher levels of estrogens and insulin than women of normal weight. Increased levels of estrogens and insulin are established risk factors for endometrial cancer,” said Inoue-Choi.

Inoue-Choi and colleagues used data from 23,039 postmenopausal women who reported dietary intake, demographic information, and medical history in 1986, prior to the cancer diagnosis, as part of the Iowa Women’s Health Study.

Dietary intake was assessed using the Harvard Food Frequency Questionnaire (FFQ), which asked study participants to report intake frequency of 127 food items in the previous 12 months.

Between 1986 and 2010, 506 type I and 89 type II endometrial cancers were recorded among the women Inoue-Choi and colleagues studied.

They did not find any association between type I or type II endometrial cancers and consumption of sugar-free soft drinks, sweets/baked goods, and starch.

Source: Indian Express

 


How to beat obesity, lifestyle diseases, by experts

EXPERTS have recommended lifestyle modifications and regular exercise as means to overcome the challenge of obesity and various complications that go along with it.

The various experts, who spoke in Lagos recently at walk against obesity exercise organized by Divine Physician and St. Luke Chaplaincy in partnership with Managed Healthcare Services (MHS) Limited, a health maintenance organization (HMO), said obesity was becoming a rampant condition among Nigerians.

Lagos University Teaching Hospital (LUTH)/College of Medicine Lagos University Teaching (CMUL) consultant endocrinologist, Dr. Sandra Iwuala, who spoke at the event, attributed the health condition to lifestyle changes which resulted from urbanization, sedentary lifestyles, dietary changes among other factors.

Iwuala warned that if not quickly handled that obesity could lead to several health risks like diabetes, hypertension, arthritis, cataract among others.

Highpoint of the event was articulated walk engaged by hundreds of children, women and men from Idi-Araba to Masha-Kilo back to Idi-Araba- a distance of several kilometers.

Managing Director of Managed Healthcare Services (MHS) Limited, Dr. Patrick Korie explained that the walk was necessary to avoid and raise awareness about obesity, a condition, which he said, is becoming prevalent among Nigerians.

The public health expert advised Nigerians to exercise at least 30 minutes three times a week to beat obesity, adding that his organization was concerned about the wellbeing of Nigerians.

Head Chaplain, LUTH-based Divine Physician and St. Luke Chaplaincy, Rev.Fr. Kwame Owiredu said the awareness was Christ-like way of looking after the physical wellbeing of people in general.

Iwuala said, “Obesity is the excessive accumulation of body fat to the extent that it may cause harmful effect to the person or affect the person’s health negatively. We usually define obesity as a body mass index (BMI) of 30 kilogram per metre square or more.

“We get that by measuring the weight of a person in kilogram and divide it by square of the height. For instance, if somebody measures 70kg and the height is 1.6, to get the BMI, we say 70 divided by 1.6 times 1.6 to get the BMI. A BMI above 30 is obesity; a BMI between 25 and 29.9 is overweight. It is not just enough to say I am not obese; my BMI is not yet 30. If your BMI is still in the overweight category, you still are still at risk of having some of the complications that obesity can bring.

“Obesity has lots of health implications. Fat is something not quiet but active; secrets hormones and doing lots of things to the body. It causes a wide range of disorders to the body, starting from the head to the toe. It can increase risk of cataract, diabetes, hypertension, stroke, asthma, sleep apnea, joint problems like osteoarthritis among others.

“Obesity is rampant because of lifestyle changes, dietary changes, urbanization so that people no longer exercise anymore; everyone wants to take bike or board a bus from point A to point B, instead of walking. Every day, we see more and more people coming down with these disorders, and obesity is one of the contributing factors. We find people whose mothers, for instance, developed diabetes at age 50 developing diabetes at 20 because of the wrong lifestyle they are living compared to the one their parents lived. We are having younger people, even at age 10, coming down with various complications of obesity.”

She urged Nigerians to check their BMI regular and live healthy lifestyles. “As individuals, we should know the category (of weight) we belong to. Check your BMI today. If your BMI is in the normal category of 18.5 to 24.9, you have to do everything to maintain it,” she said.

Source: The Guardian


Positive lifestyle changes to cut risk of metabolic syndrome

Data reported by the a new study reinforces the positive influence of lifestyle factors in mitigating risks which could potentially up heart disease risk and other health problems.

Findings based on 1,059 residents of New Ulm, Minnesota underscore the importance of obesity prevention and nutrition, specifically eating more fruits and vegetables, in addressing metabolic syndrome (MS), a common precursor to cardiovascular disease (CVD).

This study used an easily calculated Optimal Lifestyle Score (OLS), which is a composite summary of smoking, fruit and vegetable consumption, alcohol use, physical activity, and body mass index.

The results were presented by Jackie Boucher, MS, RD, LD, CDE, Vice President for Education, Minneapolis Heart Institute Foundation on Tuesday November 19 at the American Heart Association Scientific Sessions in Dallas, TX.

Boucher said that these findings clearly support national recommendations encouraging individuals to achieve energy balance and to increase fruit and vegetable consumption.

She said that their data suggests that there is a clear connection between increased body weight or the decrease in the consumption of fruits and vegetables, and the development of metabolic syndrome, a clustering of CVD risk factors.

In 2009, 1,059 of screened residents did not have MS, with 123 (12 percent) going on to develop MS by 2011.

A decline in the OLS was associated with a nearly 3-fold increased risk of incident MS (aOR = 2.9, CI: 1.69, 5.04). Changes in BMI and fruit/vegetable consumption were the OLS components most strongly associated with MS.

People who became obese during the two-year time period were more than eight times more likely to develop MS and people who reduced their intake of fruits and vegetables to less than 5 or more servings per day were four times more likely to develop MS.

Source: ANI